DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and CG43742

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001261130.1	Gene:	CG43742 / 14462622	FlyBaseID:	FBgn0263999	Length:	474	Species:	Drosophila melanogaster

Alignment Length:	234	Identity:	74/234 - (31%)
Similarity:	106/234 - (45%)	Gaps:	52/234 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 CGGALVSELYVLTAAHCATSGSKPPDM----VRLGARQLNETSATQQDIKILI-----IVLHPKY 275
            |||:|:.:.||||||||..      |:    |.||.   |..|......|.::     ::|||.:
  Fly    58 CGGSLIHKQYVLTAAHCVR------DLDEVTVHLGE---NNRSCPIPVCKHVLRLNAKVILHPNF 113

  Fly   276 RSSAYYHDIALLKLTRRVKFSEQVRPACLWQLPELQIPT-----VVAAGWGRTEFLGAKSNALRQ 335
            ..:.:.:|||||:|.|.|.|...:||.|:  :.:..:.:     ..|.|||:||. |..|:.|..
  Fly   114 HGNIFLNDIALLRLEREVIFEAHIRPICI--ILDEDVTSNNQNNFTAYGWGKTEH-GNISDVLSF 175

  Fly   336 VDLDVVPQMTCKQIYRKERRLPRGIIEGQFCAGYLPGGRDTCQGDSGGPIHALLPEYNCV----- 395
            :||..:|:..|.|..            ...|||...|  |||:.|||||:..     |.|
  Fly   176 IDLVRLPKSMCYQNI------------NTICAGSTSG--DTCESDSGGPLIG-----NFVHRGKS 221

  Fly   396 -AFVVGITSFGKFCAAPNAPGVYTRLYSYLDWIEKIAFK 433
             ..:.||||:|. .......||||.:.:|..||..:..:
  Fly   222 RDILFGITSYGD-AECSGLFGVYTDVNAYKSWIASVVLE 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	74/229 (32%)
		Tryp_SPc	186..427	CDD:214473	72/226 (32%)
CG43742	NP_001261130.1	Tryp_SPc	34..253	CDD:214473	72/226 (32%)
		Tryp_SPc	35..256	CDD:238113	74/229 (32%)
		Tryp_SPc	273..467	CDD:214473
		Tryp_SPc	273..>368	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437503
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940