DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and CG43110

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001246396.1	Gene:	CG43110 / 12798330	FlyBaseID:	FBgn0262570	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	84/253 - (33%)
Similarity:	124/253 - (49%)	Gaps:	33/253 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 VPLIVGGTPTRHGLFPHMAALGWTQGSGSKDQDIKWGCGGALVSELYVLTAAHCATSGSKPPDMV 247
            ||.|:.|:........:||.:..|         ....|||.::.|.:|||.|||.::.:.   .|
  Fly    33 VPKIISGSNASQQSAQYMAGIFNT---------THLLCGGTIIHEDFVLTVAHCKSTQTL---FV 85

  Fly   248 RLGARQLNETSATQQDIKILIIVLHPKYRSSAYYHDIALLKLTRRVKFSEQVRPACLWQLPEL-- 310
            ||||..:|..:   ..|:::..:.||:|.:|.|.:||||:||.|.|.|:..::|.|:.....|
  Fly    86 RLGAYNINHPT---DQIRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICIHLDATLGK 147

  Fly   311 QIPTVVAAGWGRTEFLGAKSNALRQVDLDVVPQMTCKQIYRKERRLPRGIIEGQFCAGYLPGGRD 375
            ||....|.|||||. ...:|:.|:::.::....|.| .:|......|:     |.||....|  |
  Fly   148 QIRYYNAFGWGRTR-NAEQSDILQRIFVNRTNPMIC-HLYLGMSPDPK-----QICATTDQG--D 203

  Fly   376 TCQGDSGGPIHALLPEYNCVAF--VVGITSFG-KFCAAPNAPGVYTRLYSYLDWIEKI 430
            ||.||||||:.:.: .|....|  ..||||:| :.|   |..|:||.:..|..||..|
  Fly   204 TCAGDSGGPLISKI-TYQGKNFDTQFGITSYGTREC---NGVGLYTDVSQYSGWIANI 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	81/248 (33%)
		Tryp_SPc	186..427	CDD:214473	79/245 (32%)
CG43110	NP_001246396.1	Tryp_SPc	35..254	CDD:214473	79/246 (32%)
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	81/248 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437519
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940