DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and gzma

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_012808240.1	Gene:	gzma / 100135014	XenbaseID:	XB-GENE-482759	Length:	267	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	89/276 - (32%)
Similarity:	122/276 - (44%)	Gaps:	61/276 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 SGKQCVPSVPLIVGGTPTRHGLFPHMAALGWTQGSGSKDQDIKWGCGGALVSELYVLTAAHCATS 239
            :|..|:.    |:.|........|:||.:....||          |||.|:.:.:|||||||..:
Frog    28 NGNICMD----IIDGREAASHSRPYMAYIYSRTGS----------CGGTLIKQNWVLTAAHCVVN 78

  Fly   240 GSKPPDMVRLGARQLNETSATQQDIKILIIVLHPKYRSSAYYHDIALLKLTRRVKFSEQVRPACL 304
            .|:    |.|||.::......||...:...:.||.:......|||.||::....|.::.|
Frog    79 NSE----VILGAHKVKSRENEQQRFSVARAIPHPCFEWKKKIHDIQLLQIKGAAKLNKFV----- 134

  Fly   305 WQLPELQIPTV----------VAAGWGRTEFLG-AKSNALRQVDLDVVPQMTCKQIYRKERRLPR 358
               ..|::||.          ..||||.|:..| ..|:.||:|::.||.:.||.:||:|   ...
Frog   135 ---SVLKLPTTDMDVKPGSSCSTAGWGVTKPNGKTPSDVLREVNVTVVDRGTCNKIYKK---FKT 193

  Fly   359 GIIEGQFCAG--------YLPGGRDTCQGDSGGPIHALLPEYNCVAFVVGITSFGKFCAAPNAPG 415
            .|.....|||        |     |.||||||||:       .|.....||.||||.|..|..||
Frog   194 EISTNMLCAGAPKKSDKKY-----DACQGDSGGPL-------ICGKEFSGIVSFGKKCGDPKYPG 246

  Fly   416 VYTRLYS-YLDWIEKI 430
            :||||.: ||.||..:
Frog   247 IYTRLTARYLQWIRDV 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	87/263 (33%)
		Tryp_SPc	186..427	CDD:214473	85/260 (33%)
gzma	XP_012808240.1	Tryp_SPc	35..262	CDD:238113	87/263 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D476534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920