DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11668 and ndl

DIOPT Version :9

Sequence 1:	NP_650254.1	Gene:	CG11668 / 41606	FlyBaseID:	FBgn0038113	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	85/346 - (24%)
Similarity:	131/346 - (37%)	Gaps:	100/346 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 HGGYLLPPPS----ISKSEQACANAYPRAHHKRRRRRRNTNPKLDQVELVEPIIQKHNQSQNLLV 149
            |..|:..||.    .|||...       .|.||.||..:     |..|:|         ....:|
  Fly  1103 HVAYVKCPPMQCGLPSKSSML-------EHSKRVRRAVS-----DSKEIV---------GDGRIV 1146

  Fly   150 GGRLTQENEHPYMCALGWPSRTNRWIHEHGSSKRRYTFNCGCAMIAPRFAITAAHCASVGGE--- 211
            ||..|...:.|::.|          |:.:|.      |:||..:.:.|:.|:||||....|:
  Fly  1147 GGSYTSALQWPFVVA----------IYRNGK------FHCGGTIYSDRWIISAAHCVINYGKYFY 1195

  Fly   212 ------------SPSVALIGGVELNSGRGQLIEIKRISQHPHFDAETLTNDLAVVKLA-----RR 259
                        ||:.             |:..:..:..|..::..::.|||::::|.     .|
  Fly  1196 EVRAGLLRRSSYSPAT-------------QIQPVSHVVVHQAYERRSMRNDLSLLRLLNPLQFNR 1247

  Fly   260 SHMPVACL-----------WNQESLPERPLTALGYGQTKFAGPHSSNLLQIMLYHLNFQQCQRYL 313
            ...|: ||           |....:.....|.:|:|..:..||.|..:.|:::      ..::..
  Fly  1248 WVKPI-CLPDKGRTTVGDDWIWGPVEHTLCTVVGWGAIREKGPSSDPMRQVIV------PIRKKC 1305

  Fly   314 HNYDKLANGLGSGQMCAGDYSGNMDTCQGDSGGPLLLHQHMRHHRHTIPYVVGITSFGGACASGQ 378
            .:.:..|    |..:||||..|..|.|||||||||...........   |:.|:.|.|..||..|
  Fly  1306 TDPEDQA----SEDICAGDPDGGRDACQGDSGGPLFCRSVSNPDEF---YLAGVVSHGNGCARPQ 1363

  Fly   379 P-GVYVRIAHYIQWIEQQVWP 398
            . |||.|:..|:.|:|....|
  Fly  1364 EFGVYTRVTLYLDWLEMATTP 1384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11668	NP_650254.1	Tryp_SPc	149..395	CDD:238113	69/277 (25%)
CG11668	NP_650254.1	Tryp_SPc	149..392	CDD:214473	67/274 (24%)
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	67/275 (24%)
		Tryp_SPc	1145..1379	CDD:238113	68/276 (25%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100