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Protein Alignment ry and Aox4

DIOPT Version :9

Sequence 1:	NP_524337.1	Gene:	ry / 41605	FlyBaseID:	FBgn0003308	Length:	1335	Species:	Drosophila melanogaster
Sequence 2:	NP_076120.2	Gene:	Aox4 / 71872	MGIID:	1919122	Length:	1336	Species:	Mus musculus

Alignment Length:	1344	Identity:	598/1344 - (44%)
Similarity:	829/1344 - (61%)	Gaps:	36/1344 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVFFVNGKKVTEVSPDPECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKIRHLAV 70
            |:||||||||.|.:||||..||.:.|:.|.|.|||..|..||||||||||||.:.:..||.|...
Mouse    10 LIFFVNGKKVIEKNPDPEKNLLFYTRKVLNLTGTKYSCGTGGCGACTVMVSRYNPKTRKIHHYPA 74

  Fly    71 NACLTPVCSMHGCAVTTVEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRNAEQPS 135
            .|||.|:|.:||.|:|||||:||.|.|:|||||||||.||:|||||:||:|||:|.||||..:|:
Mouse    75 TACLVPICWLHGAAITTVEGVGSIKKRVHPVQERLAKCHGTQCGFCSPGMVMSIYTLLRNHPEPT 139

  Fly   136 MRDLEVAFQGNLCRCTGYRPILEGYKTFT-KEFACGM--GEKCCKVSGKGC--GTDAETDDKLFE 195
            ...:..|..||||||||||||:|..|||: |...|.|  ..|||....:.|  ..:.:...||:.
Mouse   140 PDQITEALGGNLCRCTGYRPIVESGKTFSQKSTVCQMKGSGKCCMDPDEKCLESREKKMCTKLYN 204

  Fly   196 RSEFQPLDPSQEPIFPPEL-QLSDAFDSQSLIFSSDRVTWYRPTNLEELLQLKAKHPAAKLVVGN 259
            ..||||.|||||||||||| ::::..:.:.|.|...|.||..|..|.:||:|||.:|.|.||:||
Mouse   205 EDEFQPFDPSQEPIFPPELIRMAEDPNKRRLTFQGKRTTWIIPVTLNDLLELKASYPEAPLVMGN 269

  Fly   260 TEVGVEVKFKHFLYPHLINPTQVKELLEIKENQDGIYFGAAVSLMEIDALLRQRIEQLPESETRL 324
            |.||..:||....||..|:|..|.||..:....:|:..||..||.::...|...:.:.|:.:|:.
Mouse   270 TTVGPGIKFNDEFYPVFISPLGVPELNLMDTTNNGVTIGAGYSLAQLKDTLDFLVSEQPKEKTKT 334

  Fly   325 FQCTVDMLHYFAGKQIRNVACLGGNIMTGSPISDMNPVLSAAGAQLEVASFVDGKLQKRSVHMGT 389
            |......|...||.||||:|.|||:..:....||:||:|:|..|.:.|.| .:||  .|.:.:..
Mouse   335 FHALQKHLRTLAGPQIRNMATLGGHTASRPNFSDLNPILAAGNATINVVS-REGK--DRQLPLNG 396

  Fly   390 GFFTGYRRNVIEAHEVLLGIHFRKTTPDQYIVAFKQARRRDDDIAIVNAAINVRFEEKSNIVAEI 454
            .|........::..||:|.|....|...|::...:.|:|:::..|||||.::|.|||.:|.:.::
Mouse   397 PFLEKLPEADLKPEEVILSIFIPYTAQWQFVSGLRLAQRQENAFAIVNAGMSVEFEEGTNTIKDL 461

  Fly   455 SMAFGGMAPTTVLAPRTSQLMVGQEWSHQLVERVAESLCTELPLAASAPGGMIAYRRALVVSLFF 519
            .|.||.:|||.|.|.:|.:.::|::|..|::....:.:..|:.:...|.|||:.|||.|::||.|
Mouse   462 KMFFGSVAPTVVSASQTCKQLIGRQWDDQMLSDACQLVLQEIRIPPDAEGGMVEYRRTLIISLLF 526

  Fly   520 KAYLAISLKLSKSGITSSDALPSEERSGAETFHTPVLKSAQLFERVCSDQPICDPIGRPKVHAAA 584
            |.||.:...|::........:|.:..|..:.|.....:..|:|:.|...||..||:|.|.:|.:.
Mouse   527 KFYLKVQRWLNEMDPQKFPDIPGKFVSALDDFPIETPQGIQMFQCVDPKQPQKDPVGHPIMHQSG 591

  Fly   585 LKQATGEAIYTDDIPRMDGEVYLAFVLSTKPRAKITKLDASEALALDGVHQFFCYKDL---TEHE 646
            :|.||||||:.||:|.:|.|:.||.|.||:..||||.||.|||||..||......:|:   .:|.
Mouse   592 IKHATGEAIFIDDMPPIDQELCLAVVTSTRAHAKITSLDVSEALACPGVVDVITAEDVPGENDHN 656

  Fly   647 NEVGPVFHDEHVFAAGEVHCYGQIVGAIAADNKALAQRAARLVKVEYEELSPVIVTIEQAIEHKS 711
            .|:        ::|..||.|.|||:..:|||....|:.||:.||:.|:::.|.|:|||:|:||.|
Mouse   657 GEI--------LYAQSEVICVGQIICTVAADTYIHAKEAAKRVKIAYDDIEPTIITIEEALEHNS 713

  Fly   712 YF-PDYPRFVTKGNVEEALAQADHTFEGTCRMGGQEHFYLETHAALAVPRDSD-ELELFCSTQHP 774
            :. |:  :.:.:|||:.|....|...||...:.||||||:||...||:|:..| |:.|...||.|
Mouse   714 FLSPE--KKIEQGNVDYAFKHVDQIVEGEIHVEGQEHFYMETQTILAIPQTEDKEMVLHLGTQFP 776

  Fly   775 SEVQKLVAHVTALPAHRVVCRAKRLGGGFGGKESRGISVALPVALAAYRMGRPVRCMLDRDEDML 839
            :.||:.|:....:|..|:.|..||.||.||||.::...:....|:||.:.|||:|.:|:|.:|||
Mouse   777 THVQEFVSAALNVPRSRIACHMKRAGGAFGGKVTKPALLGAVCAVAANKTGRPIRFILERSDDML 841

  Fly   840 ITGTRHPFLFKYKVGFTKEGLITACDIECYNNAGWSMDLSFSVLERAMFHFENCYRIPNVRVGGW 904
            ||..|||.|.|||:||...|.|.|.|:|.|.|.|.:.|.|..|:|..:...||.|.|||.|..|.
Mouse   842 ITAGRHPLLGKYKIGFMNNGEIRAADVEYYTNGGCTPDESELVIEFVVLKSENTYHIPNFRCRGR 906

  Fly   905 VCKTNLPSNTAFRGFGGPQGMYAGEHIIRDVARIVGRDVVDVMRLNFYKTGDYTHYHQQLEHFPI 969
            .|||||||||||||||.||.....|..|..||........:|..:|.||....|.|.|.....|:
Mouse   907 ACKTNLPSNTAFRGFGFPQATVVVEAYIAAVASKCNLLPEEVREINMYKKTSKTAYKQTFNPEPL 971

  Fly   970 ERCLEDCLKQSRYDEKRQEIARFNRENRWRKRGMAVVPTKYGIAFGVMHLNQAGSLINIYGDGSV 1034
            .||.::||::|.:..:::....||..|.|:|||:||||.|:.:|..:...|||.:|::|:.||||
Mouse   972 RRCWKECLEKSSFFARKKAAEEFNGNNYWKKRGLAVVPMKFSVAVPIAFYNQAAALVHIFLDGSV 1036

  Fly  1035 LLSHGGVEIGQGLNTKMIQCAARALGIPSELIHISETATDKVPNTSPTAASVGSDLNGMAVLDAC 1099
            ||:|||.|:||||:|||||.|:|.|.:|...:|.|||:|..|||::.||.|:|:|:||.||.:||
Mouse  1037 LLTHGGCELGQGLHTKMIQVASRELNVPKSYVHFSETSTTTVPNSAFTAGSMGADINGKAVQNAC 1101

  Fly  1100 EKLNKRLAPIKEALPGGTWKEWINKAYFDRVSLSATGFYAMPGIGYHPETNPNAR-----TYSYY 1159
            :.|..||.||....|.|.|:|||..|:.:.:||||||::.    ||  :||.:.:     .|.||
Mouse  1102 QILMDRLRPIIRKNPKGKWEEWIKMAFEESISLSATGYFK----GY--QTNMDWKKEEGDPYPYY 1160

  Fly  1160 TNGVGVTVVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEELMYSPQGM 1224
            ..|...:.||:|||||.|::|.|||.:|...|:|||:||||:||||:||.|.:|.|||.|||:|:
Mouse  1161 VYGAACSEVEVDCLTGAHKLLRTDIFVDAAFSINPALDIGQVEGAFIQGMGFYTTEELKYSPKGV 1225

  Fly  1225 LYSRGPGMYKLPGFADIPGEFNVSLLTGAPNPRAVYSSKAVGEPPLFIGSSAFFAIKEAIAAARE 1289
            ||||||..||:|...:||.||.|:|: .:.||.|:||||.:||..:|:|||..|||.:|:..||:
Mouse  1226 LYSRGPEDYKIPTITEIPEEFYVTLV-HSRNPIAIYSSKGLGEAGMFLGSSVLFAIYDAVTTARK 1289

  Fly  1290 DQGLSGDFPLEAPSTSARIRIACQDKFTELLEIPEPGSFTPWNI 1333
            ::|||..|||.:|:|...||:||.|:|||::...:|.:||||:|
Mouse  1290 ERGLSDIFPLNSPATPEVIRMACTDQFTEMIPRDDPSTFTPWSI 1333

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.