Protein Alignment ry and F15E6.6

DIOPT Version :10

• Sequence 1: NP_524337.1
• Gene: ry / 41605
• FlyBaseID: FBgn0003308
• Length: 1335
• Species: Drosophila melanogaster
• Sequence 2: NP_500531.2
• Gene: F15E6.6 / 177192
• WormBaseID: WBGene00017487
• Length: 1256
• Species: Caenorhabditis elegans
• Alignment Length: 1384
• Identity: 479/1384 - (34%)
• Similarity: 696/1384 - (50%)
• Gaps: 215/1384 - (15%)

  Fly     7 VFF-VNGKKVTEVSPDPECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKIRHLAV 70
            :|| ||||.:.|.:.|||.||..:||.||.|.||||||.||.||:|||::...|...||..:.||
 Worm     6 IFFNVNGKDIKEENVDPELTLAYYLRNKLGLRGTKLGCEEGVCGSCTVVLGTWDDSLNKAVYSAV 70

  Fly    71 NACLTPVCSMHGCAVTTVEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRNAEQPS 135
            ||||.|:..:|...|.||||:|| :.::||:|:|:|:.|..|||||:||.|||.||||||...|:
 Worm    71 NACLVPLFHVHKTFVITVEGVGS-RDKIHPIQDRMARGHAVQCGFCSPGFVMSAYALLRNHPNPT 134

  Fly   136 MRDLEVAFQGNLCRCTGYRPILEGYKTFTKEFACGMGEKCC--KVSGKGCGTDAETDDKLFER-- 196
            :..:..|.:.|||||||||||||...:|:..     |..||  |.:|.||..|..::|:.:|:
 Worm   135 IEQINAAIRANLCRCTGYRPILEALYSFSSS-----GGGCCGGKKAGAGCCKDLSSEDEAYEKLT 194

  Fly   197 --SEFQPLDPSQEPIFPPELQLSDAFDSQS-LIFSSDRVTWYRPTNLEELLQLKAKHPAAKLVVG 258
              ::|...|||||.||||.|::  ..||:: :....||:....|.::|:..:.|..    :.|:.
 Worm   195 SFNDFPEYDPSQEIIFPPSLRI--FVDSENPVTLKGDRIELLLPKSIEQFKEFKKD----RTVIS 253

  Fly   259 NTEVGVEVKF------KHFLYPHLINPTQVKELLEIKENQDGIYFGAAVSLMEIDALLRQRIEQL 317
            :   |:..:|      |.| ....|....|||..|:.||.:.:..||||::.::..:|.:.:.|.
 Worm   254 S---GLITRFIATRNPKEF-SQKWITTKYVKEFNEVIENPETVVIGAAVNIQKMSDILSRSLSQN 314

  Fly   318 PESETRLFQCTVDMLHYFAGKQIRNVACLGGNIMTGS----PISDMNPVLSAAGA---------- 368
            ...|...|      :..|:..||.|.|...|.|::|:    .:||:..:.:...|
 Worm   315 IGKEVDAF------IKKFSSPQIANFATWTGGIVSGAKSSISVSDLLLLFNVLNAKLTLLTDSGD 373

  Fly   369 --QLEVASFVDGKLQKRSVHMGTGF---FTGYRRNVIEAHEVLLGIHFRKTTPDQYIVAFKQARR 428
              |:.:..||:.||...:..:.|.|   .||                        .:...|....
 Worm   374 LTQVNIEEFVEKKLFATNTIVNTVFSSSITG------------------------QLFCLKLGET 414

  Fly   429 RDDDIAIVNAAINVRFEEKSNIVAEISMAFGGMAPTTVLAPRTSQLMVGQEWSHQLVERVAESLC 493
            .:.|....|.|..|     .|.::.|.:..||       .|:  :|...:|....|.......||
 Worm   415 SEQDSTSFNFAALV-----GNNISRIFVGLGG-------PPK--RLTSLEEHIFALKNLDVPDLC 465

  Fly   494 TELPLAASAPGGM-------IAYRRALVVSLFFKAYLAISLKLSKSGITSSDAL-------PSEE 544
                    ...||       ||..|   :|.|.|       .:.|:..| .|.|       |:|.
 Worm   466 --------KTSGMGENKNIKIALTR---LSKFMK-------NVEKTAET-VDGLNYLQYFKPTER 511

  Fly   545 RSGAETFHTPVLKSAQLFERVCSDQPICDPIGRPKVHAAALKQATGEAIYTDDIPRMDGEVYLAF 609
            :|                            :|||..:....:..||||:|.:||...: .|:|.|
 Worm   512 KS----------------------------VGRPLANYFNERAITGEALYVNDIQTYN-PVHLGF 547

  Fly   610 VLSTKPRAKITKLDASEALALDGVHQFFCYKDLTEHENEVG--------PVFHDEHVFAAGEVHC 666
            ||||.|.|:|..:||:|||.|:||..||...|:..: |..|        |  .|..:||..:|..
 Worm   548 VLSTVPHAEILSIDATEALKLEGVVGFFGASDVPGN-NSPGLQISNMNLP--DDATIFADKKVES 609

  Fly   667 YGQIVGAIAADNKALAQRAARLVKVEYEELSPVIVTIEQAIEHKSYFPDYPRF-VTKGNVEEALA 730
            .||:||.|||::..||:|||:|||:||:|| |.:|.::.||..||.......| .::..|.|:|.
 Worm   610 VGQVVGVIAANDVLLARRAAKLVKLEYKEL-PALVELKDAIVAKSLLGKVRHFGKSEYLVNESLV 673

  Fly   731 QADHTFEGTCRMGGQEHFYLETHAALAVPRDSDELELFCSTQHPSEVQKLVAHVTALPAHRVVCR 795
            .:....||...:|.||||||||.::|.:|.:.||..:.||||..|..|.:||....:|||:::.:
 Worm   674 HSYKVLEGESSLGSQEHFYLETQSSLVIPGEGDESIVHCSTQGTSFTQLMVAETMKIPAHKIIVK 738

  Fly   796 AKRLGGGFGGKESRGISVALPVALAAYRMGRPVRCMLDRDEDMLITGTRHPFLFKYKVGFTKEGL 860
            .||:||.||||.:....:|...::.|.::.||....|.|:||:.|||.||....||:||...:|.
 Worm   739 TKRMGGAFGGKLNNASWIACICSVVAKKLNRPTYGYLSREEDLAITGKRHGVYTKYRVGINSDGK 803

  Fly   861 ITACDIECYNNAGWSMDLSFSVLERAMFHF-ENCYRIPNVRVGGWVCKTNLPSNTAFRGFGGPQG 924
            :.....:.:.|.|||.|.:..| ...|..| ::.|.:..||..|:..|||..|||||||:|.||.
 Worm   804 VQGIHHQAWLNGGWSKDHTEGV-TMVMGQFVDDVYNMGTVRYDGYPVKTNTNSNTAFRGYGNPQA 867

  Fly   925 MYAGEHIIRDVARIVGRDVVDVMRLNF-------YKTGD-YTHYHQQLEHFPIERCLEDCLKQSR 981
            ....|.::|.:||.||:...:|.:|||       |.:|: |:..|       || |.|.|.:.|.
 Worm   868 KLVSEGVMRRIAREVGKSTEEVKKLNFAFEGEKRYLSGNIYSDAH-------IE-CWEYCTRWSD 924

  Fly   982 YDEKRQEIARFNRENRWRKRGMAVVPTKYGIA------FGVMHLNQAGSLINIYGDGSVLLSHGG 1040
            ::::::.|..||:.::..|||:|:...:..::      .||     |..:||:  |||:.||.||
 Worm   925 FEKRKETIENFNKTSKIVKRGIAMSSVRLALSHPGPPGHGV-----ASLMINL--DGSIQLSIGG 982

  Fly  1041 VEIGQGLNTKMIQCAARALGIPSELIHISETATDKVPNTSPTAASVGSDLNGMAVLDACEKLNKR 1105
            .|:|||||.||:|..:.||..|.:.|.|.:.:|||:.|...|.||..:|.||:|||..||::..|
 Worm   983 TEMGQGLNQKMLQVCSEALKRPIDTITIVDCSTDKITNAPETGASHNADTNGLAVLACCERIMSR 1047

  Fly  1106 LAPIKEALPGGTWKEWINKAYFDRVSLSATGFYAMP----GIGYHPETNPNARTYSYYTNGVGVT 1166
            |.||.:. ..|.|::.|..||...|.|..|.:.::.    .||..        .|.|.|.|....
 Worm  1048 LQPIIDK-NDGDWEKSIRDAYGAYVPLQCTEYGSVDREKLSIGEF--------EYPYNTTGACAV 1103

  Fly  1167 VVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEELMYSPQ-GMLYSRGP 1230
            .:|:|.:||.:::|..|||||:|.|||||||||||||||||||||.|.|::.::.: |.|.....
 Worm  1104 EMEVDTMTGYNRLLRVDIVMDVGESLNPAIDIGQIEGAFMQGYGLVTCEKITFNKETGQLNQNSA 1168

  Fly  1231 GMYKLPGFADIPGEFNVSLL-TGAPNPRAVYSSKAVGEPPLFIGSSAFFA-IKEAIAAAREDQGL 1293
            |.||:|..:|:|.:|.|.|| ....|...|||||.:|||||.:...|..: |...|...|::.|:
 Worm  1169 GQYKIPKSSDVPKDFRVKLLGINKANGAKVYSSKGIGEPPLMMSCGAVHSCIMNCIDDWRKENGI 1233

  Fly  1294 SGDFPLEAPSTSARIRIAC 1312
            .......:|.::.:|:..|
 Worm  1234 DKFVDTISPLSADKIQELC 1252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ry	NP_524337.1	PLN02906	25..1317	CDD:215491	469/1365 (34%)
F15E6.6	NP_500531.2	PLN02906	23..1253	CDD:215491	470/1367 (34%)