Protein Alignment ry and LOC100495429

DIOPT Version :10

• Sequence 1: NP_524337.1
• Gene: ry / 41605
• FlyBaseID: FBgn0003308
• Length: 1335
• Species: Drosophila melanogaster
• Sequence 2: XP_012825683.2
• Gene: LOC100495429 / 100495429
• XenbaseID: XB-GENE-29082699
• Length: 1323
• Species: Xenopus tropicalis
• Alignment Length: 1348
• Identity: 642/1348 - (47%)
• Similarity: 879/1348 - (65%)
• Gaps: 46/1348 - (3%)

  Fly     1 MSNSVLVFFVNGKKVTEVSPDPECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKI 65
            :.:..|:|||||:|:.|.:.|||..||.:||:||.|.|||.||..|||||||||||.:...:.||
 Frog     5 VDSHTLIFFVNGRKIVEENADPEELLLPYLRKKLLLTGTKYGCGGGGCGACTVMVSTIHPVSKKI 69

  Fly    66 RHLAVNACLTPVCSMHGCAVTTVEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRN 130
            .|.:.||||.|:|||||.||||:||||||.|:|||||||:||||||||||||||:|||:|:||||
 Frog    70 LHFSANACLLPICSMHGAAVTTIEGIGSTTTKLHPVQERIAKAHGSQCGFCTPGMVMSVYSLLRN 134

  Fly   131 AEQPSMRDLEVAFQGNLCRCTGYRPILEGYKTFTKEFACGMGEKCCKVSGKGCG--TDAETDDK- 192
            ..:|:|..:..:..||||||||||||::|.:||     |...: ||:|...|..  :..:|.|.
 Frog   135 HPEPTMEQIYESLGGNLCRCTGYRPIVDGCRTF-----CNKTD-CCQVKENGMEKISTPDTVDNI 193

  Fly   193 ---LFERSEFQPLDPSQEPIFPPELQLSDAFDSQSLIFSSDRVTWYRPTNLEELLQLKAKHPAAK 254
               ||:..:|.||||:||.||||||.|.|....:.|||...|:||..|::|:|||||||.:|.|.
 Frog   194 LTGLFKEEQFLPLDPTQELIFPPELLLMDKEKKEKLIFQGGRMTWISPSSLQELLQLKATYPKAP 258

  Fly   255 LVVGNTEVGVEVKFKHFLYPHLINPTQVKELLEIKENQDGIYFGAAVSLMEIDALLRQRIEQLPE 319
            ||||||.||.|:||:...:|.:|:|:::.||..:....|||..|||.||..:...|::.:.|.||
 Frog   259 LVVGNTIVGPEMKFRGIFHPVIISPSRIPELNFVIHKDDGITVGAACSLTVLKEALKEVVTQQPE 323

  Fly   320 SETRLFQCTVDMLHYFAGKQIRNVACLGGNIMTGSPISDMNPVLSAAGAQLEVASFVDGKLQKRS 384
            .:|:||...:..|....|.||||.|.|||||::.||.||:||||:|....|.||: :||   .|.
 Frog   324 EKTKLFHALLQQLETLGGPQIRNTASLGGNIISRSPTSDLNPVLAAGNCILTVAA-IDG---TRQ 384

  Fly   385 VHMGTGFFTGYRRNVIEAHEVLLGIHFRKTTPDQYIVAFKQARRRDDDIAIVNAAINVRFEEKSN 449
            :.:...||.    :.::|.|||:.:|...:....:...|:||:||::.:.||.|.:.|:|||.::
 Frog   385 MPLDEAFFA----HSLKAEEVLVSVHLPYSKKGDHYSVFRQAQRRENALPIVTAGMKVQFEENTD 445

  Fly   450 IVAEISMAFGGMAPTTVLAPRTSQLMVGQEWSHQLVERVAESLCTELPLAASAPGGMIAYRRALV 514
            |:..|.:.:||:.||||.|..|.|.::|:.|...::......:..|:.|:.||||||:.||..|.
 Frog   446 IIKVIRIFYGGVGPTTVFAKTTCQDLIGKHWDDHMLSEACRLMVHEITLSPSAPGGMVEYRSTLT 510

  Fly   515 VSLFFKAYLAISLKLSKSGITSSDALPSEERSGAETFHTPVLKSAQLFERVCSDQPICDPIGRPK 579
            :|.|||.||.:..:|:..|...||.      |...:|.|...::.||::.|.|.|.:.||||||.
 Frog   511 ISFFFKFYLEVLQRLNHMGTHYSDV------SALNSFETLCNENVQLYQDVSSRQSVQDPIGRPI 569

  Fly   580 VHAAALKQATGEAIYTDDIPRMDGEVYLAFVLSTKPRAKITKLDASEALALDGVHQFFCYKDLTE 644
            :|.:.:|.|||||:|.||:|.:|||::|.||.|||..|||..||.|||||..||      .|:..
 Frog   570 MHYSGIKHATGEAVYCDDMPCVDGELFLYFVTSTKAHAKIVSLDFSEALAQPGV------VDVVT 628

  Fly   645 HENEVG---PVFHDEHV--FAAGEVHCYGQIVGAIAADNKALAQRAARLVKVEYEELSPVIVTIE 704
            .|:..|   .:|.:..|  .|..:|.|.|||:.|:.||..|.|::||..|||.||.|.|||:||:
 Frog   629 TEDCPGTCKSMFEEGEVPLLAKDKVLCVGQIICAVLADTPARAKKAAAAVKVVYENLEPVILTIQ 693

  Fly   705 QAIEHKSYFPDYPRFVTKGNVEEALAQADHTFEGTCRMGGQEHFYLETHAALAVPRDSD-ELELF 768
            :||||.|:|.. .|.:..||||||...||...||...:|||||||:||.:...:|:..| |::::
 Frog   694 EAIEHNSFFKP-QRKLENGNVEEAFKSADQIQEGEIYIGGQEHFYMETQSIRVLPKGEDKEMDVY 757

  Fly   769 CSTQHPSEVQKLVAHVTALPAHRVVCRAKRLGGGFGGKESRGISVALPVALAAYRMGRPVRCMLD 833
            .|||.|:.:|.|:|.:..:|::|:.|..||:||.||||.::..::|...|:||.:..|.|||:.:
 Frog   758 VSTQDPTYIQNLIATILNVPSNRITCHVKRVGGAFGGKTTKTGNIAAITAVAANKTRRAVRCVFE 822

  Fly   834 RDEDMLITGTRHPFLFKYKVGFTKEGLITACDIECYNNAGWSMDLSFSVLERAMFHFENCYRIPN 898
            |.:||||||.|||||.||||||..:|.|||.|:..::|||.:.|.|..|:|.|:.:.::.||:||
 Frog   823 RGDDMLITGGRHPFLGKYKVGFMNDGHITAVDVAYFSNAGCTPDDSVLVVEIALMNMDSAYRLPN 887

  Fly   899 VRVGGWVCKTNLPSNTAFRGFGGPQGMYAGEHIIRDVARIVGRDVVDVMRLNFYKTGDYTHYHQQ 963
            ||..|..|||||||||||||||.||..:..|..|.:||.........|..:|.||....||:.|:
 Frog   888 VRCTGTACKTNLPSNTAFRGFGYPQAAFVTETWISEVAIKCRIPPEKVREMNLYKDISQTHFRQE 952

  Fly   964 LEHFPIERCLEDCLKQSRYDEKRQEIARFNRENRWRKRGMAVVPTKYGIAFGVMHLNQAGSLINI 1028
            :....:..|..:|:::|.|:.:|..|..||::|.|:|:|:|::|.|:.|........||.:|::|
 Frog   953 ILARTLGMCWNECMEKSSYNSRRLAIENFNKDNYWKKKGLAIIPMKFPIGSLAKFFGQAAALVHI 1017

  Fly  1029 YGDGSVLLSHGGVEIGQGLNTKMIQCAARALGIPSELIHISETATDKVPNTSPTAASVGSDLNGM 1093
            |.|||||::|||:|:|||::||::|.|:|.||||...|||.||.|..||||..:..|:|:|:|||
 Frog  1018 YLDGSVLVTHGGIEMGQGVHTKIMQIASRELGIPLSYIHICETNTSSVPNTQVSGGSLGTDVNGM 1082

  Fly  1094 AVLDACEKLNKRLAPIKEALPGGTWKEWINKAYFDRVSLSATGFYAMPGIGYHPET---NPNART 1155
            ||.:|||.|.:||.||:...|..:||||:.:||...||||||||........:.||   ||
 Frog  1083 AVKNACEILMQRLLPIRSKNPKSSWKEWVTEAYMQSVSLSATGFCRSFDRELNWETGEGNP---- 1143

  Fly  1156 YSYYTNGVGVTVVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEELMYS 1220
            ..|...||..:.||||||||||:.|.||||:|.|.|:|||:|||||||||:||.||||:|||.:|
 Frog  1144 VHYCVYGVACSEVEIDCLTGDHKNLRTDIVIDFGCSINPAVDIGQIEGAFVQGLGLFTIEELKFS 1208

  Fly  1221 PQGMLYSRGPGMYKLPGFADIPGEFNVSLLTGAPNPRAVYSSKAVGEPPLFIGSSAFFAIKEAIA 1285
            |.|:||:|||..||:|...|||.:||||||:..||..|:||||.||||.||:|||.:||||:|:.
 Frog  1209 PNGVLYTRGPAQYKIPSVRDIPEQFNVSLLSNVPNSCAIYSSKGVGEPALFLGSSIYFAIKDAVL 1273

  Fly  1286 AAREDQGLSGDFPLEAPSTSARIRIACQDKFTELLEIPEPGSFTPWNI 1333
            :||.::|:|..|.|.:|:|..:||:||.|:||:::....|||:.||.:
 Frog  1274 SARRERGMSELFTLNSPATPEKIRMACGDQFTDMIPQNVPGSYVPWAV 1321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ry	NP_524337.1	PLN02906	25..1317	CDD:215491	624/1306 (48%)
LOC100495429	XP_012825683.2	mam_aldehyde_ox	10..1323	CDD:132014	642/1343 (48%)