Protein Alignment ry and aox1

DIOPT Version :10

• Sequence 1: NP_524337.1
• Gene: ry / 41605
• FlyBaseID: FBgn0003308
• Length: 1335
• Species: Drosophila melanogaster
• Sequence 2: XP_017953036.2
• Gene: aox1 / 100379890
• XenbaseID: XB-GENE-6045207
• Length: 1322
• Species: Xenopus tropicalis
• Alignment Length: 1344
• Identity: 617/1344 - (45%)
• Similarity: 864/1344 - (64%)
• Gaps: 48/1344 - (3%)

  Fly     2 SNSVLVFFVNGKKVTEVSPDPECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKIR 66
            ::..|:|:|||:||.|.:||||..||.:||..|.|.|||.||..|||||||||:|.:...:.||.
 Frog     7 ASDYLIFYVNGRKVVEKNPDPEDMLLPYLRRNLHLTGTKYGCGGGGCGACTVMISTVHPVSKKII 71

  Fly    67 HLAVNACLTPVCSMHGCAVTTVEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRNA 131
            |....|||.|:||::|.||||.||||::.|:|||||||:||||||||||||||:|||:|.||||.
 Frog    72 HYPALACLLPICSLYGNAVTTTEGIGNSTTKLHPVQERIAKAHGSQCGFCTPGMVMSIYTLLRNH 136

  Fly   132 EQPSMRDLEVAFQGNLCRCTGYRPILEGYKTFTKEFACGMGEKCCKVSGKGCGTDAETDDKLFER 196
            .:|:|..:..|..|||||||||||||:|.|||:|:  |.:.||     .:....:.::..|||..
 Frog   137 PEPTMEQILSALSGNLCRCTGYRPILDGCKTFSKD--CCLNEK-----KEHRLEEVKSFPKLFYE 194

  Fly   197 SEFQPLDPSQEPIFPPELQLSDAFDSQSL--IFSSDRVTWYRPTNLEELLQLKAKHPAAKLVVGN 259
            .:|.||||:|:.||||||.:  .|:||..  :|..:|:|||.|:.|:|:|:||.|:|:|.|||||
 Frog   195 KDFLPLDPTQDLIFPPELMM--MFNSQKKMNVFLGERITWYSPSTLDEILELKTKYPSAPLVVGN 257

  Fly   260 TEVGVEVKFKHFLYPHLINPTQVKELLEIKENQDGIYFGAAVSLMEIDALLRQRIEQLPESETRL 324
            |.:|.::||:..::|.||:|.:|.:|..:..|..||..|||.||.::..:|.:.|..:.|.:.::
 Frog   258 TALGPQMKFQGVIHPVLISPVRVMDLYNVSLNDMGISIGAACSLSQVKEILCENISAIQEDKAKI 322

  Fly   325 FQCTVDMLHYFAGKQIRNVACLGGNIMTGSPISDMNPVLSAAGAQLEVASFVDGKLQKRSVHMGT 389
            |...:..|...||:|||::|.:||:|::...|||:||:|:|.||.|..||    |.:.|.|.:..
 Frog   323 FHALLQHLGTLAGEQIRSMASIGGHIISKRTISDLNPILAAGGAILNFAS----KGETRQVELNE 383

  Fly   390 GFFTGYRRNVIEAHEVLLGIHFRKTTPDQYIVAFKQARRRDDDIAIVNAAINVRFEEKSNIVAEI 454
            .||||  .:..::.||||.:....:..|:::.||:||:|.::..|||||.:.|.|||.::||.|:
 Frog   384 LFFTG--SSPQKSEEVLLSVFIPYSKKDEFVSAFRQAQRDENANAIVNAGMKVHFEEDTDIVKEM 446

  Fly   455 SMAFGGMAPTTVLAPRTSQLMVGQEWSHQLVERVAESLCTELPLAASAPGGMIAYRRALVVSLFF 519
            ::.:|.|.|:||.|..|||.::|:.|..:::....:.:..|:.|:.|||||.:.|||||.:|.||
 Frog   447 AIYYGCMGPSTVYAKNTSQALIGRHWDEEMLNEACKLILEEITLSPSAPGGKVQYRRALTISFFF 511

  Fly   520 KAYLAISLKLSKSGITSSDALPSEERSGAETFHTPVLKSAQLFERVCSDQPICDPIGRPKVHAAA 584
            |.||.: |:..|..|.|| ::.|:..|..:.|.....|:.|:|:....:|||.||:|.|.||.:.
 Frog   512 KFYLQV-LQCLKKTIKSS-SVASDYISAIKDFEINTPKTLQIFQETEQEQPIDDPVGHPIVHTSG 574

  Fly   585 LKQATGEAIYTDDIPRMDGEVYLAFVLSTKPRAKITKLDASEALALDGVHQFFCYKDLTEHENEV 649
            :|||||||||.||:|.:|.|:::|||.|.:..|||..:||||||||.||......:|: ..:||:
 Frog   575 IKQATGEAIYVDDMPTVDQELFIAFVTSKRAHAKILSIDASEALALPGVCDIIRAEDI-PGKNEL 638

  Fly   650 GPVFHDEHVFAAGEVHCYGQIVGAIAADNKALAQRAARLVKVEYEELSPVIVTIEQAIEHKSYFP 714
            ..:   .|:|:..:|.|.|||:.|:.||....|::||..||::|:.|.|||:|:|.||::.|:|.
 Frog   639 DGL---NHLFSEDKVECVGQIICAVVADTPKHAKQAAAKVKIDYQNLEPVILTMEDAIKNNSFFE 700

  Fly   715 DYPRFVTKGNVEEALAQADHTFEGTCRMGGQEHFYLETHAALAVPR-DSDELELFCSTQHPSEVQ 778
            ...:.: .||.|||...|||..||...:||||.||:||:..|.||: :.:||:::.|||.|:.||
 Frog   701 PEKKII-HGNAEEAFKSADHILEGEVHIGGQEQFYMETNTVLVVPKGEENELDIYVSTQDPTGVQ 764

  Fly   779 KLVAHVTALPAHRVVCRAKRLGGGFGGKESRGISVALPVALAAYRMGRPVRCMLDRDEDMLITGT 843
            ..||....:|::||:|..||:||.||||.::....|...|:||::..|||||:|:|.||||||..
 Frog   765 LAVAACLNVPSNRVMCHVKRVGGAFGGKITKPSIFACASAVAAHKTKRPVRCVLERGEDMLITAG 829

  Fly   844 RHPFLFKYKVGFTKEGLITACDIECYNNAGWSMDLSFSVLERAMFHFENCYRIPNVRVGGWVCKT 908
            ||||..||||||..:|.|...|:..|.|||.|.|.|..||..|:...:|.|..||:......|||
 Frog   830 RHPFFGKYKVGFMNDGRIVGLDVSFYTNAGCSTDESILVLVVALIKMDNAYHFPNLTCTATACKT 894

  Fly   909 NLPSNTAFRGFGGPQGMYAGEHIIRDVARIVGRDVVDVMRLNFYKTGDYTHYHQQLEHFPIERCL 973
            ||||||||||||.||.....|.|:..||...|.....|...|.|.....|||:|:.:...:.||.
 Frog   895 NLPSNTAFRGFGFPQTGLVTETIMDAVAVKCGLQPHQVREKNMYTGIGKTHYNQEFDSTNLMRCW 959

  Fly   974 EDCLKQSRYDEKRQEIARFNRENRWRKRGMAVVPTKYGIAFGVMHLNQAGSLINIYGDGSVLLSH 1038
            .:|:::|.|..:|..|..||:||.|:|:|:|::|.|:.:.|.....:||.:|::||.||.||:||
 Frog   960 NECMQKSSYQSRRDAIQEFNKENYWKKKGIAIIPLKFTVGFVEKTYHQAAALVHIYRDGYVLVSH 1024

  Fly  1039 GGVEIGQGLNTKMIQCAARALGIPSELIHISETATDKVPNTSPTAASVGSDLNGMAVLDACEKLN 1103
            .|||:||||.||::|..:|.|.||...|:|.||:|..|||:..:..|:|:|:.|:||.:||:.|.
 Frog  1025 SGVEMGQGLYTKIVQVVSRELKIPMSYIYICETSTVTVPNSIASGGSIGTDITGIAVKNACDILQ 1089

  Fly  1104 KRLAPIKEALPGGTWKEWINKAYFDRVSLSATGFYAMPGIGYHPETNPNARTY-----------S 1157
            :||.||....|.|.|:||:::|:..|:|||:||:|.    ||.        ||           .
 Frog  1090 QRLEPIISRNPNGKWEEWVSEAFEQRISLSSTGYYR----GYD--------TYMDWEKGEGHAGP 1142

  Fly  1158 YYTNGVGVTVVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEELMYSPQ 1222
            ||..|...:.:|:|||||.:..|.||||||:|.|:||.|||||:||||.||:||:|.|||.|||.
 Frog  1143 YYIFGAACSEIELDCLTGKYNNLRTDIVMDLGQSINPGIDIGQVEGAFTQGFGLYTTEELQYSPF 1207

  Fly  1223 GMLYSRGPGMYKLPGFADIPGEFNVSLLTGAPNPRAVYSSKAVGEPPLFIGSSAFFAIKEAIAAA 1287
            |.||:.||..|.:|...|||.||||.||..:.||..:||||.|||..||:|.|.|||||:||.:|
 Frog  1208 GSLYTLGPDKYIMPAVCDIPREFNVYLLASSNNPYTIYSSKGVGETALFLGCSVFFAIKDAIDSA 1272

  Fly  1288 REDQGLSGDFPLEAPSTSARIRIACQDKFTELLEIPEPGSFTPW 1331
            |.::|||.||.|.:|:...|||:||.|..|.::...|.|::.||
 Frog  1273 RAERGLSKDFTLNSPAGPERIRMACSDYLTNMIPKDEAGTYNPW 1316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ry	NP_524337.1	PLN02906	25..1317	CDD:215491	600/1305 (46%)
aox1	XP_017953036.2	mam_aldehyde_ox	11..1320	CDD:132014	617/1340 (46%)