Protein Alignment CtBP and GRHPR

DIOPT Version :10

• Sequence 1: NP_001262522.1
• Gene: CtBP / 41602
• FlyBaseID: FBgn0020496
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: XP_024303484.1
• Gene: GRHPR / 9380
• HGNCID: 4570
• Length: 429
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 83/319 - (26%)
• Similarity: 123/319 - (38%)
• Gaps: 71/319 - (22%)

  Fly    23 PLQARPLVALLDGRDCSIEMPILKDVATVAFCDAQSTSEIHE----------------------- 64
            |...||..|...|:       :|.....|..|.|..|...||
Human    74 PAWPRPGPATFPGQ-------LLYCQVRVGGCTADETGATHEGVRHPQDTRRGCEVEQWDSDEPI 131

  Fly    65 --KVLNEAV----GALMWHTIILTKEDLEKFKA-LRIIVRIGSGTDNIDVKAAGELGIAVCNVPG 122
              |.|...|    |.|...:..:.|..|:...| |::|..:..|.|::.:....:.||.|    |
Human   132 PAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRV----G 192

  Fly   123 YGVEEVADTT----MCLILNLYRRTYWLANMVREGKKFTGPEQVREAAHG----------CA-RI 172
            |..:.:.|||    :.|:|...||.               ||.:.|..:|          |. .:
Human   193 YTPDVLTDTTAELAVSLLLTTCRRL---------------PEAIEEVKNGGWTSWKPLWLCGYGL 242

  Fly   173 RGDTLGLVGLGRIGSAVALRAKAFGFNVIFYDPYLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHC 237
            ...|:|::||||||.|:|.|.|.||.....|....|...:.:.......:..:|..|||.:.:.|
Human   243 TQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVAC 307

  Fly   238 TLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEP 296
            :|......|.|:...::|:..|..:|.:||.:|:.:.|..||..|:|.||.|||...||
Human   308 SLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEP 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtBP	NP_001262522.1	CtBP_dh	28..342	CDD:240624	81/314 (26%)
GRHPR	XP_024303484.1	GDH	117..379	CDD:240626	71/269 (26%)