Protein Alignment CtBP and phgdh

DIOPT Version :9

• Sequence 1: NP_001262522.1
• Gene: CtBP / 41602
• FlyBaseID: FBgn0020496
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_955871.2
• Gene: phgdh / 321928
• ZFINID: ZDB-GENE-030131-647
• Length: 528
• Species: Danio rerio
• Alignment Length: 386
• Identity: 117/386 - (30%)
• Similarity: 173/386 - (44%)
• Gaps: 66/386 - (17%)

  Fly    81 LTKEDLEKFKALRIIVRIGSGTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYW 145
            :|.:.:....:|:||.|.|:|.||:||.||.:.||.|.|.|.......|:.|..|:::|.|....
Zfish    59 VTADVINAGSSLKIIGRAGTGVDNVDVDAATKRGIIVMNTPSGNTLSAAELTCALVMSLSRHIPQ 123

  Fly   146 LANMVREG----KKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVALRAKAFGFNVIFYDPY 206
            ....:::|    |||.|.|           :.|..||:|||||||..||.|.::||...|.|||.
Zfish   124 AVISMKDGKWDRKKFMGSE-----------LYGKVLGIVGLGRIGKEVATRMQSFGMKTIGYDPI 177

  Fly   207 LPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVD 271
            .|..:..|.|:.:: ||..|..|.|.:::|..|......|:|:.:..:.:.|..:||.||||::|
Zfish   178 TPPEVSASWGVEQM-TLDQLWPQCDYITVHTPLMASTTGLLNDASFAKCKKGVKVVNCARGGIID 241

  Fly   272 DETLALALKQGRIRAAALDVH-ENEPYNGALKDAPNLICTPHAAFFSDASATELREMAATEIR-- 333
            :..|..||:.|:...|.|||. |..|...||.:.||:|..||..    ||..|.:.....:|.
Zfish   242 EAALLRALESGQCGGAGLDVFVEEPPRERALVNHPNVISCPHLG----ASTKEAQARCGKDIALQ 302

  Fly   334 -------RAIVGNIPDVLRNCVNKEYFMRTPPAAAAGGVAAAVYPEG---LNGGYYTG-ALHHRA 387
                   :|:||                    |..|..:|:...|:.   :..|...| .|...:
Zfish   303 IVDMATGKALVG--------------------AVNAQVLASTFSPDSQQWIRLGESMGKVLKACS 347

  Fly   388 HSTTPHDGPHSTTNLGSTVGGGPTTVAQAAAAAVAAAAAAALLPSPVPSHLSPQ-VGGLPL 447
            .||.|....| .|:||..:        :.:...:::||...|| :..| |..|. |..|||
Zfish   348 ASTQPCSQLH-VTSLGEAL--------KKSTGFLSSAAVVGLL-TEAP-HNGPNLVNALPL 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtBP	NP_001262522.1	CtBP_dh	28..342	CDD:240624	92/274 (34%)
		LdhA	45..351	CDD:223980	92/283 (33%)
phgdh	NP_955871.2	PGDH	8..499	CDD:273556	117/386 (30%)
		PGDH_4	8..310	CDD:240650	89/266 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0111
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D305212at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3406
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850