DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8031 and MHO1

DIOPT Version :9

Sequence 1:	NP_650252.1	Gene:	CG8031 / 41601	FlyBaseID:	FBgn0038110	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_012541.1	Gene:	MHO1 / 853464	SGDID:	S000003768	Length:	338	Species:	Saccharomyces cerevisiae

Alignment Length:	335	Identity:	133/335 - (39%)
Similarity:	181/335 - (54%)	Gaps:	48/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSARRATHAGSWYTDSGAELSRQLDRWLGAADLSHGP---ARAIIAPHAGYTYCGACAAFAYRQV 62
            ||.|.||||||||::...|||:||..:|..:.|. ||   ||.||.|||||.|||...|::|..:
Yeast     1 MSIRPATHAGSWYSNRAQELSQQLHTYLIKSTLK-GPIHNARIIICPHAGYRYCGPTMAYSYASL 64

  Fly    63 S-PVVVKRIFILGPSHHVRLRGCAL-SVAKKYRTPLYDLKIDAQ-----INSELEKTGK--FSWM 118
            . ...||||||||||||:..:...| |...:..|||.:||:|..     |..|..:.||  |..|
Yeast    65 DLNRNVKRIFILGPSHHIYFKNQILVSAFSELETPLGNLKVDTDLCKTLIQKEYPENGKKLFKPM 129

  Fly   119 DMKTDEDEHSIEMHLPYIAKVM---EDYKDQFTIVPILVGSLNPEQEAQYGSLLSSYLMDPTNLF 180
            |..||..|||:||.||.:.:.:   |...|...:.|::|...:.:.:...|::||.|:.||.|||
Yeast   130 DHDTDMAEHSLEMQLPMLVETLKWREISLDTVKVFPMMVSHNSVDVDRCIGNILSEYIKDPNNLF 194

  Fly   181 VISSDFCHWGHRFSYTYYDSSCGAIH--------------------------KSIEKLDKQGMDI 219
            ::||||||||.||.||.|..|...::                          :|||.:|:..|..
Yeast   195 IVSSDFCHWGRRFQYTGYVGSKEELNDAIQEETEVEMLTARSKLSHHQVPIWQSIEIMDRYAMKT 259

  Fly   220 IESLNPH-----SFTEYLRKYNNTICGRHPIGVMLGAVKALQDQGYDKMSFKFLKYAQSSQCQDI 279
            : |..|:     ::.:||....|||||..||.|:|.|:..::|.|...:.|::..|:|||....|
Yeast   260 L-SDTPNGERYDAWKQYLEITGNTICGEKPISVILSALSKIRDAGPSGIKFQWPNYSQSSHVTSI 323

  Fly   280 EDSSVSYASG 289
            :|||||||||
Yeast   324 DDSSVSYASG 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8031	NP_650252.1	MEMO_like	5..289	CDD:153373	128/329 (39%)
MHO1	NP_012541.1	Memo	5..334	CDD:280116	130/331 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341989
Domainoid	1	1.000	201	1.000	Domainoid score	I561
eggNOG	1	0.900	-	-		E1_COG1355
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6272
Inparanoid	1	1.050	205	1.000	Inparanoid score	I831
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60655
OrthoFinder	1	1.000	-	-		FOG0004912
OrthoInspector	1	1.000	-	-		oto100342
orthoMCL	1	0.900	-	-		OOG6_101032
Panther	1	1.100	-	-	LDO	PTHR11060
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1709
SonicParanoid	1	1.000	-	-		X3464
TreeFam	1	0.960	-	-
	15	14.790