DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8031 and Memo1

DIOPT Version :9

Sequence 1:	NP_650252.1	Gene:	CG8031 / 41601	FlyBaseID:	FBgn0038110	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_038967827.1	Gene:	Memo1 / 298787	RGDID:	1309929	Length:	334	Species:	Rattus norvegicus

Alignment Length:	325	Identity:	187/325 - (57%)
Similarity:	225/325 - (69%)	Gaps:	38/325 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RRATHAGSWYTDSGAELSRQLDRWLGAADLSHGPARAIIAPHAGYTYCGACAAFAYRQVSPVVVK 68
            |.|:|||||||.||.:|:.||:.||.....:..||||||||||||||||:|||.||:||.|.:.:
  Rat     8 REASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPHAGYTYCGSCAAHAYKQVDPSITR 72

  Fly    69 RIFILGPSHHVRLRGCALSVAKKYRTPLYDLKIDAQINSELEKTGKFSWMDMKTDEDEHSIEMHL 133
            |||||||||||.|..||||....||||||||:||.:|..||.|||.|..|.::||||||||||||
  Rat    73 RIFILGPSHHVPLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFERMSLQTDEDEHSIEMHL 137

  Fly   134 PYIAKVMED-------------------------------------YKDQFTIVPILVGSLNPEQ 161
            ||.||.||.                                     :||:|||:|:|||:|:..:
  Rat   138 PYTAKAMERRSSRCLQAQEQLLRENLFVHDLSQFHFSWAVHVSSTCHKDEFTIIPVLVGALSESK 202

  Fly   162 EAQYGSLLSSYLMDPTNLFVISSDFCHWGHRFSYTYYDSSCGAIHKSIEKLDKQGMDIIESLNPH 226
            |.::|.|.|.||.||:||||:||||||||.||.|:|||.|.|.|::|||.|||.||.|||.|:|.
  Rat   203 EQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQLDPV 267

  Fly   227 SFTEYLRKYNNTICGRHPIGVMLGAVKALQDQGYDKMSFKFLKYAQSSQCQDIEDSSVSYASGSL 291
            ||:.||:||:|||||||||||:|.|:..||..|.: |||.||.|||||||:..:|||||||:|:|
  Rat   268 SFSNYLKKYHNTICGRHPIGVLLNAITELQKSGMN-MSFSFLNYAQSSQCRSWQDSSVSYAAGAL 331

Fly 292 291
Rat 332 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8031	NP_650252.1	MEMO_like	5..289	CDD:153373	184/320 (58%)
Memo1	XP_038967827.1	MEMO_like	9..331	CDD:153373	185/322 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336837
Domainoid	1	1.000	389	1.000	Domainoid score	I758
eggNOG	1	0.900	-	-		E1_COG1355
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6272
Inparanoid	1	1.050	394	1.000	Inparanoid score	I1906
OMA	1	1.010	-	-		QHG60655
OrthoDB	1	1.010	-	-		D1057950at2759
OrthoFinder	1	1.000	-	-		FOG0004912
OrthoInspector	1	1.000	-	-		oto98793
orthoMCL	1	0.900	-	-		OOG6_101032
Panther	1	1.100	-	-	LDO	PTHR11060
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3464
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810