DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8031 and SPAC4H3.04c

DIOPT Version :9

Sequence 1:	NP_650252.1	Gene:	CG8031 / 41601	FlyBaseID:	FBgn0038110	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_594340.1	Gene:	SPAC4H3.04c / 2543654	PomBaseID:	SPAC4H3.04c	Length:	309	Species:	Schizosaccharomyces pombe

Alignment Length:	308	Identity:	120/308 - (38%)
Similarity:	171/308 - (55%)	Gaps:	26/308 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RRATHAGSWYTDSGAELSRQLDRWLGAADLSHGPARAIIAPHAGYTYCGACAAFAYRQVSPVVVK 68
            |.||||||||.|....|::||..::.......| .|.:|:|||||.|.|..|:..::|:....::
pombe     6 REATHAGSWYLDDTELLTKQLKSFIKNPTPETG-KRFVISPHAGYMYSGKVASQGFQQLDFSKIQ 69

  Fly    69 RIFILGPSHHVRLRGCALSVAKKYRTPLYDLKIDAQINSEL-EKTGKFSWMDMKTDEDEHSIEMH 132
            |:|:.|||||:..|.|.:|.|....|||.|||:|..:..:| .....|..|.:..||.|||:||.
pombe    70 RVFVFGPSHHIFTRKCLVSRASICSTPLGDLKVDEDLCQKLVASDNSFDSMTLDVDESEHSLEMQ 134

  Fly   133 LPYIA--KVMEDYKDQFTIVPILVGSLNPEQEAQYGSLLSSYLMDPTNLFVISSDFCHWGHRFSY 195
            .|.:|  .:.:....:..||||::|:|...........||.|:.|.:|.|||||||||||.||.|
pombe   135 FPLLAFHLLKQGCLGKVKIVPIMIGALTSTTMMAAAKFLSQYIKDESNSFVISSDFCHWGRRFGY 199

  Fly   196 TYY------------------DSSCGAIHKSIEKLDKQGMDIIESLNPHSFTEYLRKYNNTICGR 242
            |.|                  ..:...|::||..||..||.|||:.:...|:|||:...||||||
pombe   200 TLYLNDTNQLEDAVLKYKRRGGPTSPKIYESISNLDHIGMKIIETKSSDDFSEYLKTTQNTICGR 264

  Fly   243 HPIGVMLGAVKALQDQGYDKMSFKFLKYAQSSQCQDIEDSSVSYASGS 290
            :||.:::   |:::...:.: .|||:.|||||..:.:.|||||||:.:
pombe   265 YPIELIM---KSMECANFSE-RFKFISYAQSSHVELVTDSSVSYATAT 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8031	NP_650252.1	MEMO_like	5..289	CDD:153373	119/304 (39%)
SPAC4H3.04c	NP_594340.1	Memo	7..308	CDD:280116	119/305 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	205	1.000	Domainoid score	I628
eggNOG	1	0.900	-	-		E1_COG1355
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6272
Inparanoid	1	1.050	207	1.000	Inparanoid score	I966
OMA	1	1.010	-	-		QHG60655
OrthoFinder	1	1.000	-	-		FOG0004912
OrthoInspector	1	1.000	-	-		oto102114
orthoMCL	1	0.900	-	-		OOG6_101032
Panther	1	1.100	-	-	LDO	PTHR11060
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1709
SonicParanoid	1	1.000	-	-		X3464
TreeFam	1	0.960	-	-
	14	13.860