|
Fly 46 ADAEGDVDATASSSCVATASQLNPSPPPAGVQQAKPARSSSPPCQLLERLSFPDGNIINT---LH 107
|.|.|.:.|.|..: |.....:|...|:....|...:...| ||.|....|.:.:.: ..
Rat 55 AAAHGPLGAGAGGA----AGGYFETPFSFGMNHRTPPYPAGDYC-LLCRSERKDSSFLESGVKTA 114
Fly 108 TILALPPFDPYAPAPKAETVYKEVVSLMQW----------SQREDNAIELELSDKLLHECEHKGG 162
:.||| :.|||..: |:.|..| .:...:.::....|.||| ...||
Rat 115 SKLAL------SMAPKGNS----VLHLPLWVCPDCRRTVEKEERHSGLDQPGQDFLLH--SSLGG 167
Fly 163 DPNDETRSYLMAIENMRLFSEDPKNPLRDADGQLRAITLYFQNLAFIFVKHRKEEFFTFCSCKEC 227
...:.:.:..:|:....:.|........|| |||:.|
Rat 168 SQPETSGAGRLALGTQTMTSSGLGTTPSDA-----------------------------CSCEAC 203
Fly 228 LEYRETIMAIMMDQFKAAHMVVMLLDVLIKAYSPMLKNDAAYNKFEKLLECNKEIYWITSGYLY- 291
.|.|: |.| :.|....:.:. ||....|:.
Rat 204 SERRD-----------------------ISA-----ETDREPQQLQN--------YWSEVRYMVR 232
Fly 292 ----DKNAEYLDFIDDTAISDNMILVLFSAILMANNPMLLLQ---------ILAYNVECIVKAFS 343
.......:..|.:.:.|...:......|...:|..|.| :|...|..:.:..:
Rat 233 CIYRQAGTPLAEDQDQSLVPDKEGVKELVDRLCERDPYQLYQRLEQQAREYVLEMKVRLLRQLSA 297
Fly 344 EGMIEIAQNIQENEKISAERMLTYILDGYSDLNCISQKISLSLFAFENDFLRKFRLSWVLLCQRL 408
....:....:|...: |...::.:|:.|..|...::.||..|...||:.|:||:::|.|..:.|
Rat 298 AAKAKAPSGLQGPPQ--AHHFVSLLLEEYGALCQAARSISTFLGTLENEHLKKFQVTWELHNKHL 360
Fly 409 FQQHVFT-PLGDTMLACILSLKEVAPSAQTT-------ALIKRYMLFDEHMHSIERRWTDIWIEL 465
|:..||: ||..:.|..::|...:..:...| .|::||...:|.: |:..:.|:|.
Rat 361 FENLVFSEPLLQSNLPALVSQIRLGTTTHDTCNEDMYSTLLQRYQRSEEEL----RKVAEEWLEC 421
Fly 466 NKFNLSPTEHERRMGLLDVYNIFDKVVLDATSFSLPDISDDEFIDFQRIVDRQLAWKNI------ 524
.| .:|.| :.:::.:......|.: |.|....:|:::.||..|.:
Rat 422 QK-------------RIDAY-VDEQMTMKTKQRMLTE--DWEIFKQRRLIEEQLTNKKVVTGENN 470
Fly 525 -------MAFTKLKWPDGFYDPPNKLVHEDLCKKCNSLLEHHNENCKC--------ITCSIAGTP 574
|..::|..|| |..|| :...|.| :||.|..||
Rat 471 FTDTRRHMLSSRLSMPD--------------CPNCN-----YRRRCACDDCSLSHILTCGIMDTP 516
Fly 575 -----------------------LRPRQ-------AGHCAKCTTLGIVEKDPKLM---KSKILST 606
:||.. :|..:..| :::.|:|: .....:.
Rat 517 VTDDIHIHQLPLQVDSAPDYLSEMRPPSVSSASSGSGSSSPIT----IQQHPRLILTDNGSAPTF 577
Fly 607 CTSDE------AK------------------------------HNAAI------AATTSSSTSTA 629
|:.|| || .|.|: .::||.|:|.|
Rat 578 CSDDEDVAPLSAKFADIYPLTNYDDTNVVANMNGIHSELNGGGENMALKDESPQVSSTSRSSSEA 642
Fly 630 QQQRRTSD-------LPEDESPTGSGSSGSVFRRQAETSDTLRTTYHIAWAVFQHLATRKRYRHE 687
..:...:: .|:.|...|:|:. |.:....:|...:|. |.:......
Rat 643 DDEEADAESSGEPPGAPKQEEAIGNGNP----RTEESKVNTPPPSYP---------AQQAEQTPN 694
Fly 688 TIEPQFICGENCRVSACQLARKILSNQLSPLLTKYLLRCFQPLSFTREELR-----------STI 741
|.| | ..|:..|..|....::....|...::| .|...|...|. .|:
Rat 695 TCE----C-HVCKQEASGLPASAMTAGALPPGHQFL----SPEKPTHPALHLYPHIHGHVPLHTV 750
Fly 742 PSL-------------MFFNRKLAPSPAELQELRNQHYVYKTYWTFVLSIYANFFVKFNSSSTDF 793
|.| .|.:.|..| ||.:|...|:... ||:|..|
Rat 751 PHLPRPLIHPTLYPAPPFTHSKALP-PAPVQSHTNKPQA------------------FNASLQD- 795
Fly 794 GHLELIKGDLRLRLNSVVGDKEDNRFEQFLAQVIGYSPFKVTDDFTLGDANIEKLQF------GV 852
|: ..|..|:..|....:|:: :.:...:.|.|.....| |.
Rat 796 -HI----------YPSCFGNTPDWNSSKFIS---------LWESEMMNDKNWNPGTFLPDTISGS 840
Fly 853 DQLMMLHDSQIIKRTKPDSTTGLSGAKSKLGESNVPQSGGKNGEAGGNKKSKEK--MRKCCSDYA 915
|.| ..::..|:|:: :|........|..:.|.|:. .:||..::.
Rat 841 DIL-----GPVLSETRPEA---------------LPPPPSNEAPAVSDIKEKKNAAKKKCLYNFQ 885
Fly 916 DIGEPCKENHSKKRVKKECNHARFNE--TRDRLRKKLSQI-VNERKTKST------------EET 965
|......|......|....:.|..:. |...::...||. |:.|:..|. ..:
Rat 886 DAFMEANEVAMANTVAMATSSATSSVSCTATTVQSSSSQFKVSSRRPPSIGDVFHGLNKEDHRHS 950
Fly 966 TPSKTKCS----KPEPVAVP---APAAIP-------PKRP-----------------PSPFNPPK 999
.|:..:.| .|.|...| :||:.| |..| |:|..||.
Rat 951 APAAPRNSPTGLAPLPALSPSALSPASTPHLPNLAAPSFPKTATTAPGFVDTRKSFCPTPVAPPP 1015
Fly 1000 LPAVLAVAALDRICR----EEH----------EDDSLLRLDSLCKSLQRHTDATDAS-------- 1042
.....:::|...:|. |.| :||.....|. .|...|:.:|..|
Rat 1016 STTDGSISAPPSVCSDPDCEGHRCENGVYDPQQDDGDESADE--DSCSEHSSSTSTSTNQKEGKY 1078
Fly 1043 AAAAALAAFKHGSGFPA-----DYS-------------KEDM---MQDFAEFLGTYTYTREQDQQ 1086
........|.|| |.|| :|: ||:. |:..:|..|...:.|.:|..
Rat 1079 CDCCYCEFFGHG-GPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMEQISEREGVVDHRRVEDLL 1142
Fly 1087 RWINETLNFIEGKSQQPHTANPKKAAKKAKQKMRK--------------------EEEKRIKELE 1131
::|| |.:....:..:|||:|:.|.|| ||:|:.:|.|
Rat 1143 QFIN---------SSEAKPVSSSRAAKRARHKQRKLEEKARLEAEARAREHLHHQEEQKQREEEE 1198
Fly 1132 DLRCQFLDIYFK-EFIDKYEMKTLTAAGGRKKEK--KRIGELETNIKNLQRAKAKVETVILELIA 1193
:...:..:..|| ||....|::.|.||..:||:: |...:|:...:|.|
Rat 1199 EEEEEDEEQRFKEEFQRLQELQKLRAAKKKKKDRPSKDCSKLDMLARNFQ--------------- 1248
Fly 1194 TVKQTNSEFKFSYLPTKQQQLAKMAQLEEILNGGPTTATAEPVRQEPPQQSAPQYPEFSSNASFY 1258
|..||: ||:...
Rat 1249 -------------------------------------AATEPI----------------SNSENI 1260
Fly 1259 HPPGLGQQNTPVCFAPPQQSQHPPQLSRDVIAAMAASSITADPSKRIVTIRRVQLPHPGAEQQVT 1323
|...|.|.. .|:.|.|.|....: .::|. |.|||....|
Rat 1261 HNGSLEQTE------EPETSSHSPSRHMN----------HSEPR-----------PGPGANGDAT 1298
Fly 1324 VVAKGSAPHEDKLLY-TFVNG--------------HMVASGPIQPEEMAPRQATVPAPAPSVPEK 1373
.... |.:.|||. ..||| |.......|..:...:.::.||..|:.|.|
Rat 1299 DPVD---PRDSKLLLPKEVNGKQHEPLAFLLDMMHHHKEGNSKQKLKQTSKASSEPARKPTEPPK 1360
Fly 1374 SAKAKKKEAKRAAAAAAAEAAAAAEAAAAAAAEAAAEQKAKL-------KNKKQAKKTAVAVATA 1431
:.:.:.| ..|..|.|.|: :.|::.:|
Rat 1361 TTEVQLK------------------------PRAQPELKPKVVDLALLTEQKREERK-------- 1393
Fly 1432 SSSTASSNSSKSQTPQSTRESSVCSVKPKTVPKKPTSKPPKVVEVTPPPPVPE-----------P 1485
|.|:|::|.|......| |:..|||.||.|. .
Rat 1394 ---TNSNNNNKKQLSHIKEE--------------------KLSTVTPEPPSPSQHLQNGRLILAS 1435
Fly 1486 EPEPPKRQKRLKSR 1499
.|:|..:.|:.|.:
Rat 1436 SPQPKGKNKKNKKK 1449
| 
