Protein Alignment CG7518 and Fam193a

DIOPT Version :9

• Sequence 1: NP_731761.3
• Gene: CG7518 / 41599
• FlyBaseID: FBgn0038108
• Length: 2464
• Species: Drosophila melanogaster
• Sequence 2: XP_038948753.1
• Gene: Fam193a / 305452
• RGDID: 1309634
• Length: 1516
• Species: Rattus norvegicus
• Alignment Length: 1769
• Identity: 312/1769 - (17%)
• Similarity: 522/1769 - (29%)
• Gaps: 689/1769 - (38%)

  Fly    46 ADAEGDVDATASSSCVATASQLNPSPPPAGVQQAKPARSSSPPCQLLERLSFPDGNIINT---LH 107
            |.|.|.:.|.|..:    |.....:|...|:....|...:...| ||.|....|.:.:.:   ..
  Rat    55 AAAHGPLGAGAGGA----AGGYFETPFSFGMNHRTPPYPAGDYC-LLCRSERKDSSFLESGVKTA 114

  Fly   108 TILALPPFDPYAPAPKAETVYKEVVSLMQW----------SQREDNAIELELSDKLLHECEHKGG 162
            :.|||      :.|||..:    |:.|..|          .:...:.::....|.|||  ...||
  Rat   115 SKLAL------SMAPKGNS----VLHLPLWVCPDCRRTVEKEERHSGLDQPGQDFLLH--SSLGG 167

  Fly   163 DPNDETRSYLMAIENMRLFSEDPKNPLRDADGQLRAITLYFQNLAFIFVKHRKEEFFTFCSCKEC 227
            ...:.:.:..:|:....:.|........||                             |||:.|
  Rat   168 SQPETSGAGRLALGTQTMTSSGLGTTPSDA-----------------------------CSCEAC 203

  Fly   228 LEYRETIMAIMMDQFKAAHMVVMLLDVLIKAYSPMLKNDAAYNKFEKLLECNKEIYWITSGYLY- 291
            .|.|:                       |.|     :.|....:.:.        ||....|:.
  Rat   204 SERRD-----------------------ISA-----ETDREPQQLQN--------YWSEVRYMVR 232

  Fly   292 ----DKNAEYLDFIDDTAISDNMILVLFSAILMANNPMLLLQ---------ILAYNVECIVKAFS 343
                .......:..|.:.:.|...:......|...:|..|.|         :|...|..:.:..:
  Rat   233 CIYRQAGTPLAEDQDQSLVPDKEGVKELVDRLCERDPYQLYQRLEQQAREYVLEMKVRLLRQLSA 297

  Fly   344 EGMIEIAQNIQENEKISAERMLTYILDGYSDLNCISQKISLSLFAFENDFLRKFRLSWVLLCQRL 408
            ....:....:|...:  |...::.:|:.|..|...::.||..|...||:.|:||:::|.|..:.|
  Rat   298 AAKAKAPSGLQGPPQ--AHHFVSLLLEEYGALCQAARSISTFLGTLENEHLKKFQVTWELHNKHL 360

  Fly   409 FQQHVFT-PLGDTMLACILSLKEVAPSAQTT-------ALIKRYMLFDEHMHSIERRWTDIWIEL 465
            |:..||: ||..:.|..::|...:..:...|       .|::||...:|.:    |:..:.|:|.
  Rat   361 FENLVFSEPLLQSNLPALVSQIRLGTTTHDTCNEDMYSTLLQRYQRSEEEL----RKVAEEWLEC 421

  Fly   466 NKFNLSPTEHERRMGLLDVYNIFDKVVLDATSFSLPDISDDEFIDFQRIVDRQLAWKNI------ 524
            .|             .:|.| :.:::.:......|.:  |.|....:|:::.||..|.:
  Rat   422 QK-------------RIDAY-VDEQMTMKTKQRMLTE--DWEIFKQRRLIEEQLTNKKVVTGENN 470

  Fly   525 -------MAFTKLKWPDGFYDPPNKLVHEDLCKKCNSLLEHHNENCKC--------ITCSIAGTP 574
                   |..::|..||              |..||     :...|.|        :||.|..||
  Rat   471 FTDTRRHMLSSRLSMPD--------------CPNCN-----YRRRCACDDCSLSHILTCGIMDTP 516

  Fly   575 -----------------------LRPRQ-------AGHCAKCTTLGIVEKDPKLM---KSKILST 606
                                   :||..       :|..:..|    :::.|:|:   .....:.
  Rat   517 VTDDIHIHQLPLQVDSAPDYLSEMRPPSVSSASSGSGSSSPIT----IQQHPRLILTDNGSAPTF 577

  Fly   607 CTSDE------AK------------------------------HNAAI------AATTSSSTSTA 629
            |:.||      ||                              .|.|:      .::||.|:|.|
  Rat   578 CSDDEDVAPLSAKFADIYPLTNYDDTNVVANMNGIHSELNGGGENMALKDESPQVSSTSRSSSEA 642

  Fly   630 QQQRRTSD-------LPEDESPTGSGSSGSVFRRQAETSDTLRTTYHIAWAVFQHLATRKRYRHE 687
            ..:...::       .|:.|...|:|:.    |.:....:|...:|.         |.:......
  Rat   643 DDEEADAESSGEPPGAPKQEEAIGNGNP----RTEESKVNTPPPSYP---------AQQAEQTPN 694

  Fly   688 TIEPQFICGENCRVSACQLARKILSNQLSPLLTKYLLRCFQPLSFTREELR-----------STI 741
            |.|    | ..|:..|..|....::....|...::|    .|...|...|.           .|:
  Rat   695 TCE----C-HVCKQEASGLPASAMTAGALPPGHQFL----SPEKPTHPALHLYPHIHGHVPLHTV 750

  Fly   742 PSL-------------MFFNRKLAPSPAELQELRNQHYVYKTYWTFVLSIYANFFVKFNSSSTDF 793
            |.|             .|.:.|..| ||.:|...|:...                  ||:|..|
  Rat   751 PHLPRPLIHPTLYPAPPFTHSKALP-PAPVQSHTNKPQA------------------FNASLQD- 795

  Fly   794 GHLELIKGDLRLRLNSVVGDKEDNRFEQFLAQVIGYSPFKVTDDFTLGDANIEKLQF------GV 852
             |:          ..|..|:..|....:|::         :.:...:.|.|.....|      |.
  Rat   796 -HI----------YPSCFGNTPDWNSSKFIS---------LWESEMMNDKNWNPGTFLPDTISGS 840

  Fly   853 DQLMMLHDSQIIKRTKPDSTTGLSGAKSKLGESNVPQSGGKNGEAGGNKKSKEK--MRKCCSDYA 915
            |.|     ..::..|:|::               :|........|..:.|.|:.  .:||..::.
  Rat   841 DIL-----GPVLSETRPEA---------------LPPPPSNEAPAVSDIKEKKNAAKKKCLYNFQ 885

  Fly   916 DIGEPCKENHSKKRVKKECNHARFNE--TRDRLRKKLSQI-VNERKTKST------------EET 965
            |......|......|....:.|..:.  |...::...||. |:.|:..|.            ..:
  Rat   886 DAFMEANEVAMANTVAMATSSATSSVSCTATTVQSSSSQFKVSSRRPPSIGDVFHGLNKEDHRHS 950

  Fly   966 TPSKTKCS----KPEPVAVP---APAAIP-------PKRP-----------------PSPFNPPK 999
            .|:..:.|    .|.|...|   :||:.|       |..|                 |:|..||.
  Rat   951 APAAPRNSPTGLAPLPALSPSALSPASTPHLPNLAAPSFPKTATTAPGFVDTRKSFCPTPVAPPP 1015

  Fly  1000 LPAVLAVAALDRICR----EEH----------EDDSLLRLDSLCKSLQRHTDATDAS-------- 1042
            .....:::|...:|.    |.|          :||.....|.  .|...|:.:|..|
  Rat  1016 STTDGSISAPPSVCSDPDCEGHRCENGVYDPQQDDGDESADE--DSCSEHSSSTSTSTNQKEGKY 1078

  Fly  1043 AAAAALAAFKHGSGFPA-----DYS-------------KEDM---MQDFAEFLGTYTYTREQDQQ 1086
            ........|.|| |.||     :|:             ||:.   |:..:|..|...:.|.:|..
  Rat  1079 CDCCYCEFFGHG-GPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMEQISEREGVVDHRRVEDLL 1142

  Fly  1087 RWINETLNFIEGKSQQPHTANPKKAAKKAKQKMRK--------------------EEEKRIKELE 1131
            ::||         |.:....:..:|||:|:.|.||                    ||:|:.:|.|
  Rat  1143 QFIN---------SSEAKPVSSSRAAKRARHKQRKLEEKARLEAEARAREHLHHQEEQKQREEEE 1198

  Fly  1132 DLRCQFLDIYFK-EFIDKYEMKTLTAAGGRKKEK--KRIGELETNIKNLQRAKAKVETVILELIA 1193
            :...:..:..|| ||....|::.|.||..:||::  |...:|:...:|.|
  Rat  1199 EEEEEDEEQRFKEEFQRLQELQKLRAAKKKKKDRPSKDCSKLDMLARNFQ--------------- 1248

  Fly  1194 TVKQTNSEFKFSYLPTKQQQLAKMAQLEEILNGGPTTATAEPVRQEPPQQSAPQYPEFSSNASFY 1258
                                                 |..||:                ||:...
  Rat  1249 -------------------------------------AATEPI----------------SNSENI 1260

  Fly  1259 HPPGLGQQNTPVCFAPPQQSQHPPQLSRDVIAAMAASSITADPSKRIVTIRRVQLPHPGAEQQVT 1323
            |...|.|..      .|:.|.|.|....:          .::|.           |.|||....|
  Rat  1261 HNGSLEQTE------EPETSSHSPSRHMN----------HSEPR-----------PGPGANGDAT 1298

  Fly  1324 VVAKGSAPHEDKLLY-TFVNG--------------HMVASGPIQPEEMAPRQATVPAPAPSVPEK 1373
            ....   |.:.|||. ..|||              |.......|..:...:.::.||..|:.|.|
  Rat  1299 DPVD---PRDSKLLLPKEVNGKQHEPLAFLLDMMHHHKEGNSKQKLKQTSKASSEPARKPTEPPK 1360

  Fly  1374 SAKAKKKEAKRAAAAAAAEAAAAAEAAAAAAAEAAAEQKAKL-------KNKKQAKKTAVAVATA 1431
            :.:.:.|                        ..|..|.|.|:       :.|::.:|
  Rat  1361 TTEVQLK------------------------PRAQPELKPKVVDLALLTEQKREERK-------- 1393

  Fly  1432 SSSTASSNSSKSQTPQSTRESSVCSVKPKTVPKKPTSKPPKVVEVTPPPPVPE-----------P 1485
               |.|:|::|.|......|                    |:..|||.||.|.           .
  Rat  1394 ---TNSNNNNKKQLSHIKEE--------------------KLSTVTPEPPSPSQHLQNGRLILAS 1435

  Fly  1486 EPEPPKRQKRLKSR 1499
            .|:|..:.|:.|.:
  Rat  1436 SPQPKGKNKKNKKK 1449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7518	NP_731761.3	None
Fam193a	XP_038948753.1	PHA03247	<951..1026	CDD:223021	15/74 (20%)
		PRK12704	<1106..>1183	CDD:237177	17/85 (20%)
		FAM193_C	1460..1515	CDD:406363

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354262
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2C6D2
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008017
OrthoInspector	1	1.000	-	-		oto98859
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15109
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930