Protein Alignment CG7488 and ERAL1

DIOPT Version :10

• Sequence 1: NP_650248.1
• Gene: CG7488 / 41597
• FlyBaseID: FBgn0038106
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_005693.1
• Gene: ERAL1 / 26284
• HGNCID: 3424
• Length: 437
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 110/369 - (29%)
• Similarity: 186/369 - (50%)
• Gaps: 47/369 - (12%)

  Fly    31 GAAHTNDAVAPTTRPPPAESRNPGEE-------------QRSLHIAVIGVPNVGKSTFINNTVNH 82
            |.:..:.:|.|..   ||.|.|..|:             .|.|.:.::|.||.||||..|..:..
Human    75 GFSQPDSSVTPCV---PAVSMNRDEQDVLLVHHPDMPENSRVLRVVLLGAPNAGKSTLSNQLLGR 136

  Fly    83 RVCPTSAKVHTTRQSNTAIYTTGQTQLVFYDTPGLVTQHEIRRHHLDQNFKSAYRHAIQHADIIA 147
            :|.|.|.||||||.....:.|..:||::..||||:::..:.:||||:.:.......:::.||::.
Human   137 KVFPVSRKVHTTRCQALGVITEKETQVILLDTPGIISPGKQKRHHLELSLLEDPWKSMESADLVV 201

  Fly   148 VVHDASNAWTRKELHPTVLDTLKAYSNLPSFLVLNKIDALKSKRLLLDLIKTLTNDTLTVGKREV 212
            |:.|.|:.|||.:|.|.:|..|..||.:||.||:||:|.||.|.:||:|...||...:...|.::
Human   202 VLVDVSDKWTRNQLSPQLLRCLTKYSQIPSVLVMNKVDCLKQKSVLLELTAALTEGVVNGKKLKM 266

  Fly   213 Q----------AKSALAKEIRI----NKRESSWSHFSDVFLVSALTGNGLQEMQNYLVGQAKPRD 263
            :          ..|...|:...    |.:...|.||.::|::|||:...::.::.||:.||:|..
Human   267 RQAFHSHPGTHCPSPAVKDPNTQSVGNPQRIGWPHFKEIFMLSALSQEDVKTLKQYLLTQAQPGP 331

  Fly   264 WKYPADIHTDSSPEALIVESVRARLLDYLPQEIPYNLKCEIEYYSVEKNVVY---------TSVQ 319
            |:|.:.:.|..:||.:....:|.:||::||||:|||::        :|..|:         ...:
Human   332 WEYHSAVLTSQTPEEICANIIREKLLEHLPQEVPYNVQ--------QKTAVWEEGPGGELVIQQK 388

  Fly   320 VQCPTTRIERLICGEGNGKLRQITERVTSDLVEMFGQAVSLTIS 363
            :..|.....:|:.|.....:.||.:....||:::|...|.:.:|
Human   389 LLVPKESYVKLLIGPKGHVISQIAQEAGHDLMDIFLCDVDIRLS 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7488	NP_650248.1	Era	57..259	CDD:206726	72/215 (33%)
		KH-II_Era	282..363	CDD:411791	21/89 (24%)
ERAL1	NP_005693.1	era	116..434	CDD:234624	100/325 (31%)