DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment yellow-f and yellow-c

DIOPT Version :9

Sequence 1:	NP_524335.1	Gene:	yellow-f / 41595	FlyBaseID:	FBgn0041710	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001285947.1	Gene:	yellow-c / 34879	FlyBaseID:	FBgn0041713	Length:	438	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	172/457 - (37%)
Similarity:	247/457 - (54%)	Gaps:	53/457 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLSLDVLLLCAISGFQLLISADGDPMIEVFKWKQLDFYNRGDGYKDLWNRICIPDSHFYNSRKCL 65
            ||||. |::|.|..|..:.||   .:.|.|.||||.|.         |.   .|::.       .
  Fly     6 MLSLG-LMVCLIGAFSRIASA---KLEEKFSWKQLAFD---------WP---TPEAE-------A 47

  Fly    66 GSSSSGSFIQYNNVPQGVTHFRGRLFVTVPRRQPGIPSTLNYIDLAKDGWSQSPHLRAYPNLAVN 130
            .:.|:|.:|..||:|.||..::.|:||||||.:.|:.:||||||:  :...:||.|..||:...|
  Fly    48 EAKSNGHYIVENNLPLGVERWQNRIFVTVPRWKAGVAATLNYIDI--NSTEKSPKLHPYPSWEAN 110

  Fly   131 QYNASEQ----------------------------NLVSVYRTSVDVCGRLWFVDTGMLEFPNNR 167
            :.....|                            .::|.:|..||||.|||.:|||:.:...:.
  Fly   111 KLPIDVQPQDQKTPSGGRLDADKAQDAGIQLKDNSTVISTFRIQVDVCDRLWVLDTGLADILGSP 175

  Fly   168 QQIRHPSIWVIDLANDRLLKRFEIPQSIVEIGRGLASITIDVGARRCNDAYAYIPDLVNRRLHVY 232
            :||...||.|.||..|.||:||.||....:.....|:|.:|.....|.||:||||||....:.||
  Fly   176 KQITPNSILVFDLKTDTLLRRFTIPADQTKEDSFFANIVVDADRSECQDAFAYIPDLGAYGVIVY 240

  Fly   233 HLRSDRIWSFEHSFFNFDPLSDNLNIGGQTFRWDDGIFSATLGSYKPDGSRDVFFHPMASTNEFV 297
            .||:|:.:..:|:||:||||..:.|:||..|:|.||:|...:|...||.|:|::||.:|||.||.
  Fly   241 SLRNDKSYRVKHNFFHFDPLHGDFNVGGVNFQWTDGVFGLAVGPMNPDHSKDIYFHALASTKEFK 305

  Fly   298 VSNRVLQQEFNAARSDHGDDFHLLGTRGPSTQSTMHKYDPRTGVIFFAEVQKSGVGCWKTSKPFS 362
            |||||||.|.:....|...||..:|.||.:.|||...:||.|||||:.:|.|..:.||...:|::
  Fly   306 VSNRVLQNESHVTAGDSYYDFKYVGDRGMNGQSTAEVFDPETGVIFYTQVNKDAIACWNIKRPYT 370

  Fly   363 TENHGSVYSNSSEMIYPSDLTIDEEGYIWVMSNSMPIFVYSKLDVEKYNFRIWRQSTLLAKRGTV 427
            .:..|.:.|:|..:::|:|:.||.||.|||:|:.||.::|.:||....|:||.........:||.
  Fly   371 PDTQGLIDSDSHTLVFPNDMKIDNEGTIWVLSDKMPTYLYKELDPSAVNYRILMGQNRDLIKGTP 435

  Fly   428 CE 429
            ||
  Fly   436 CE 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yellow-f	NP_524335.1	MRJP	140..428	CDD:281074	122/287 (43%)
yellow-c	NP_001285947.1	MRJP	148..436	CDD:281074	122/287 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3386
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D940689at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10009
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850