Protein Alignment CG31342 and Apba3

DIOPT Version :10

• Sequence 1: NP_001097763.1
• Gene: CG31342 / 41592
• FlyBaseID: FBgn0051342
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_006241080.1
• Gene: Apba3 / 83611
• RGDID: 620846
• Length: 636
• Species: Rattus norvegicus
• Alignment Length: 797
• Identity: 137/797 - (17%)
• Similarity: 233/797 - (29%)
• Gaps: 341/797 - (42%)

  Fly   216 PAPPPEPPTSPVPTTPAPPAPAPAAMSNTLTQHLLNMLSDPISTYSEQISESVESASGQEDVAVA 280
            |..||.|||..:.....|..|:....|||                        :.|.|
  Rat     7 PQHPPGPPTMDLEEPKGPEVPSEDHPSNT------------------------QWALG------- 40

  Fly   281 EEPPAEQPTTSDADLNLSDDEYLSPLLRKACMLTE-------NGARVDVVVVTGQRVSADQVL-- 336
               |....|.|:.:|:.|.   :..|:::...|..       :||...:.:.|||.::..:.|
  Rat    41 ---PRGPDTLSEMELDTSS---VRALVQQLEALPSDLGGQFPDGAPCPLHIATGQGLATQENLDA 99

  Fly   337 -----------NLEHILQCERLIPRPQTSRSMSAGAADKSKRPQRKPLQSQSSSAAP-----TNS 385
                       ||..:|:||..:| .|:.....|.||.:..:|...|      ...|     |..
  Rat   100 GGLLSAEAGGDNLLGLLRCEASLP-AQSVPPDPAQAAPRLLQPPEDP------GGDPGWMEGTEP 157

  Fly   386 ADSQDNITIIQVSNTANSGQEHPPELPPKNTTTAEVFRFPEVKSKPQTNAKQQPIQTHHEYKSNV 450
            ||::.:                                    .|.|:...:..|:.||.:
  Rat   158 ADNRSS------------------------------------SSSPELWLETAPLVTHRD----- 181

  Fly   451 QIIPSNASSSTSTIQVLGKQSSSSNPYTTPVKQSSSNGSSSQVSGTTKVKVLGDGDATTKVAVYG 515
               |...:.|..|:                    :|..:.|:|.|....:.|.||      .::|
  Rat   182 ---PPVGTQSQETL--------------------ASCPAVSEVPGPCGQEELMDG------VLFG 217

  Fly   516 TCYPAAGGSAPSSSAASSSVNPAKPQTPRLSKKIILSANTSGITNISVNTEQGSDSIISGNIHYE 580
            ..|       ..|:...|..||  |.:.|:.:                 .::..|.:.:.....:
  Rat   218 AKY-------LGSTQLLSERNP--PPSTRMGQ-----------------AQEAMDRVKAPEGETQ 256

  Fly   581 -----KVFLSSS-IPITSRSSPTRVAN--TNTTQPVTNGSPAL---PRRRLASPATAQPVTPNAA 634
                 .:|:|:. :.:.:..|...:.:  ..|...:.:..|.|   .|||||...|:|.
  Rat   257 PMTEVDIFISTKRVKVLAADSQDALMDHALQTISYIADIGPVLVLMARRRLAKRTTSQD------ 315

  Fly   635 GRATPQLTRGLTELVISSRPSRRDFHYLKLLNTPLKTKTSHKSTSAANNNIEQSTPSSSNSTQVT 699
              ...||.:.|..:          ||
  Rat   316 --RQRQLYKMLCHV----------FH--------------------------------------- 329

  Fly   700 PTQRNNTSIVTGDSQEQRRRSSSTSDAQAPLQRVPQP---ATQRNANNNEFTPSRNGAFRMQPPP 761
                                   :.|||...|.:.|.   |..:....|...||:.|   |||..
  Rat   330 -----------------------SEDAQLIAQAIGQAFSIAYSQFLQENRIDPSQVG---MQPSA 368

  Fly   762 QGTPP---------SSTNPAQQSPNKRLTLREQQVMQLRREIMHPG-GVRLNLRRKDCVGSIAWV 816
            ..:.|         :|.|..:....||                 || |:           .:|.|
  Rat   369 SASHPHNGDLDHFCNSQNCREVCIQKR-----------------PGEGL-----------GVALV 405

  Fly   817 EAFGGVWIAGW-KQKEHPVLYNALH-----------IGDQL-----LSIAGVSISSAAEANKIIR 864
            |       :|| ......|:.|.||           |||::     .|:.|:|:::...|.:.:|
  Rat   406 E-------SGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVR 463

  Fly   865 NTNTLFVEVLLRRIPFGRAYAIRRDREGQCLGL-IRDGNTSTIVDVVPNSLAARHGLPPKTQSCD 928
            ..:::.:.::  ..|......|.|....:.||. :.:|   .|..::..|.|.|.|:....:
  Rat   464 RHSSVTLSII--HCPPVTTAVIHRPHVREQLGFCVENG---IICSLLRGSAAERGGVRVGHR--- 520

  Fly   929 GNSLTFWMLTEINGRSL 945
                    :.|:||:|:
  Rat   521 --------IIEVNGQSV 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31342	NP_001097763.1	PHA03247	<589..785	CDD:223021	34/212 (16%)
		PDZ_canonical	<838..866	CDD:483948	10/43 (23%)
		PDZ_canonical	879..969	CDD:483948	15/68 (22%)
Apba3	XP_006241080.1	PTB_X11	208..359	CDD:269919	37/262 (14%)
		PDZ1_APBA1_3-like	388..473	CDD:467203	22/119 (18%)
		PDZ_canonical	477..545	CDD:483948	14/67 (21%)