DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31342 and SDCBP2

DIOPT Version :9

Sequence 1:	NP_001097763.1	Gene:	CG31342 / 41592	FlyBaseID:	FBgn0051342	Length:	994	Species:	Drosophila melanogaster
Sequence 2:	NP_001186713.1	Gene:	SDCBP2 / 27111	HGNCID:	15756	Length:	292	Species:	Homo sapiens

Alignment Length:	233	Identity:	61/233 - (26%)
Similarity:	105/233 - (45%)	Gaps:	38/233 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   761 PQG--TPPSSTNPAQQ-SP--NKRLTLREQQVMQLRREIM----HPGGVRLNLRRKDCVGSIAWV 816
            |:|  |..|...|.|. :|  ...|.:|..::....|||.    ..|...|.||:.|
Human    71 PEGDSTAVSGPGPGQMVAPVTGYSLGVRRAEIKPGVREIHLCKDERGKTGLRLRKVD-------- 127

  Fly   817 EAFGGVWIAGWKQKEHPVLYNALHIGDQLLSIAGVSIS--SAAEANKIIRNTNTLFVEVLLRRIP 879
               .|:::. ..|...|.....|..|||||.|.|...:  |:.:|:::::..:...:.|::|..|
Human   128 ---QGLFVQ-LVQANTPASLVGLRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIVVVVRDRP 188

  Fly   880 FGRAYAIRRDREGQCLGLIRDGNTSTIVDVVPNSLAARHGLPPKTQSCDGNSLTFWMLTEINGRS 944
            |.|...:.:|..|....:|:.|.   ||.:|..|.|||:||           ||...:.|::|::
Human   189 FQRTVTMHKDSMGHVGFVIKKGK---IVSLVKGSSAARNGL-----------LTNHYVCEVDGQN 239

  Fly   945 LNLFFKDFEIRDRLNSVGRDISILVQPSDLITKLKKQL 982
            : :..||.:|.:.|.:.|..:::.:.||.:...:.|:|
Human   240 V-IGLKDKKIMEILATAGNVVTLTIIPSVIYEHMVKKL 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31342	NP_001097763.1	PDZ	886..973	CDD:214570	23/86 (27%)
SDCBP2	NP_001186713.1	PDZ	117..185	CDD:238080	19/79 (24%)
SDCBP2	NP_001186713.1	PDZ_signaling	191..264	CDD:238492	23/87 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12345
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4935
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.040