Protein Alignment CG31342 and apba1

DIOPT Version :10

• Sequence 1: NP_001097763.1
• Gene: CG31342 / 41592
• FlyBaseID: FBgn0051342
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_004910830.1
• Gene: apba1 / 100485825
• XenbaseID: XB-GENE-977639
• Length: 924
• Species: Xenopus tropicalis
• Alignment Length: 994
• Identity: 179/994 - (18%)
• Similarity: 307/994 - (30%)
• Gaps: 295/994 - (29%)

  Fly   206 RVVAPSHQAPPAPP--PEPPTSP-------------VPTTPAPPAPAPAAMSNTLTQHLLNMLSD 255
            |.:..|..:|.|.|  |...|||             .||..|...|.......:..|........
 Frog     2 RYLQDSSLSPSAAPRLPTKLTSPHHHHTHKQAASVLDPTVQALGYPLRVTSLESCGQRAFGAEQR 66

  Fly   256 PISTYSEQISESVESASGQEDVAVAEEP-PAEQPTTSDADLNLSDDE-----YLSPLLRKA---- 310
            .:...:.....::....|.::|.|::|| .|:...:.:|||...:.|     ::.|.||:.
 Frog    67 CLYYKTYCCEPAMNHLEGSQEVEVSDEPGSADINESVEADLEHPEVEEEQHQFVPPNLRQVSEEQ 131

  Fly   311 --------------CMLTENG-------ARVDVVVVTGQRVSADQVLNLEHILQCERLIPRPQTS 354
                          ...||:|       |..||:.|.......|::                |.:
 Frog   132 EGQSGQEEDGTLARSASTESGFHNHTDTAEGDVIAVQADGYDVDRI----------------QEN 180

  Fly   355 RSMSAGAADKSKRPQRKPLQSQSSSAAPTNSADSQDNITI-----------IQVSNTANSG---- 404
            ...||.|.      |.:|...:.:..|.....::..|.|:           .:..|.|.||
 Frog   181 DDESAYAI------QYRPESEEYTENAEAEHGEALHNRTLPNHLHFHGLDQEEALNAAYSGYVYT 239

  Fly   405 ---------------------QEH-------PPELPPKNTTTAEVFRFPEVKSKPQTNAKQQPIQ 441
                                 |||       .|||..:     |..|..|.:.:...|.:::.:.
 Frog   240 HRLFHRGEDEQYAEPYADYGLQEHVYEEIGDTPELDIR-----EGLRLYEQEREEADNYRKEALG 299

  Fly   442 T---HHEYKSN---------VQIIPSNASSSTSTIQVLGKQSSSSNPYTTPVKQSSSNGSSSQVS 494
            .   |::.:|:         .:..|.....|.       :|....:.....||||.|:.|..:|:
 Frog   300 ARLHHYDERSDGESDSPEKEAEFAPYPRMDSY-------EQEEDIDQIVAEVKQSMSSQSLDKVA 357

  Fly   495 ----------GTTKVKVLGDGDATTKVAVYGTCYPAAGGSAPSSSAASSSVNPAK---------- 539
                      ...:...||.|...|            .|:..|.|..|:|....:
 Frog   358 EDMPEAEQNLDIVEPSKLGGGSHVT------------NGNLSSCSKTSTSTGEVQRYSKEKRDAI 410

  Fly   540 ---------------------PQTPRLSKKIILSANTSGITNISVNTEQGSDSIISGNI------ 577
                                 |.||...|:.|....    .:||...:......:.|:|
 Frog   411 SLAIKDIKEAIEEVKTRTVRSPYTPDEPKEPIWVMR----QDISPTKDCDDQRPLGGDINALNDM 471

  Fly   578 ----HYEKVFLSSSIPITSRSSPTRVANT------NTTQPVTNGSPALPRRRLASPATAQPVTPN 632
                :|:..:.....|....|||....:|      |......:.|....|:.|||    .|....
 Frog   472 ENFWNYQADYRDEDSPSPDSSSPQGAESTNRQNHQNACDAAESSSNKESRKSLAS----FPTYVE 532

  Fly   633 AAGRATPQ-LTRGL---------TELVISSRPSRRDFHYLKLLNTPLKTKTSHKSTSAANNNIEQ 687
            ..|...|: |..|:         |:|:....|| ::...::......:.|.:.|...:.....|.
 Frog   533 VPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPS-KNVRMMQAQEAVSRIKMAQKLAKSRKKAAEG 596

  Fly   688 STPSSSNSTQVTPTQRNNTSIVTGDSQEQR-----RRSSSTSD-----AQAPLQRVPQPATQRNA 742
            .....:.......|||  ..::..|:||..     |..|..:|     .....:|:|:..:|.:.
 Frog   597 EAQPMTEVDLFISTQR--IKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQDSV 659

  Fly   743 NNNEFTPSRNG--AFRM--------------QPPPQG--------TPPSSTNPAQQSPNKRLTLR 783
            ..:.  ||::|  .::|              |...|.        ...:..||...|..:...|.
 Frog   660 EASH--PSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLL 722

  Fly   784 EQQVMQLRREIMHPG------GVRLNLRRKDCVGSI----AWVEAFGGVWIAGWKQKEHPVLYNA 838
            ..|.| ...:::|..      .|.:..::.:.:|.:    .|......|.||.............
 Frog   723 NTQDM-YNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGK 786

  Fly   839 LHIGDQLLSIAGVS-----ISSAAEANKIIRNTNTLFVEVLLRRIPFGRAYAIRRDREGQCLGL- 897
            |.||||::||.|.|     :|:.....|.::|.:.:.:.::  |.|......|||......||.
 Frog   787 LSIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIV--RCPPVTTVLIRRPDLRYQLGFS 849

  Fly   898 IRDGNTSTIVDVVPNSLAARHGLPPKTQSCDGNSLTFWMLTEINGRSLNLFFKDFEIRDRLNSVG 962
            :::|   .|..::...:|.|.|:....:           :.||||:|:.....:..:....|:||
 Frog   850 VQNG---IICSLMRGGIAERGGVRVGHR-----------IIEINGQSVVATPHEKIVHILSNAVG 900

  Fly   963 RDISILVQPSDLITKLKKQ 981
             :|.:...|:.:...|..|
 Frog   901 -EIHMKTMPAAMYRLLTAQ 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31342	NP_001097763.1	PHA03247	<589..785	CDD:223021	45/245 (18%)
		PDZ_canonical	<838..866	CDD:483948	11/32 (34%)
		PDZ_canonical	879..969	CDD:483948	20/90 (22%)
apba1	XP_004910830.1	Mint1_CID	407..452	CDD:439308	7/48 (15%)
		PTB_X11	539..710	CDD:269919	28/175 (16%)
		PDZ1_APBA1_3-like	742..827	CDD:467203	18/84 (21%)
		PDZ2_APBA1_3-like	831..908	CDD:467255	19/91 (21%)