DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Paip2 and PAIP2

DIOPT Version :9

Sequence 1:	NP_001262515.1	Gene:	Paip2 / 41591	FlyBaseID:	FBgn0038100	Length:	124	Species:	Drosophila melanogaster
Sequence 2:	NP_001028284.1	Gene:	PAIP2 / 51247	HGNCID:	17970	Length:	127	Species:	Homo sapiens

Alignment Length:	126	Identity:	50/126 - (39%)
Similarity:	70/126 - (55%)	Gaps:	20/126 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LKVPSVDWTDQIIYVVDDDESL---SDIDDEPDFSEYMWMENEEEFDKNELQRLEEEEIMQECFE 64
            :|.||...|...|  :::|..:   |..||.| |:|||||||||||::...:.|.|||.::.||:
Human     1 MKDPSRSSTSPSI--INEDVIINGHSHEDDNP-FAEYMWMENEEEFNRQIEEELWEEEFIERCFQ 62

  Fly    65 AMIEDELEEQINEW-----EKAKT-----DEQNTALSALPKSQCD-VEKSVLNPMADEFVP 114
            .|:|   ||:.:||     :..:|     |:.|..:.:...|..| |.||.|||.|.||||
Human    63 EMLE---EEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVP 120

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Paip2	NP_001262515.1	PAM2	102..117	CDD:399847	10/13 (77%)
PAIP2	NP_001028284.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24		6/24 (25%)
		PABPC1-interacting motif-1 (PAM1)	22..75		28/56 (50%)
		PABPC1-interacting motif-2 (PAM2)	105..120		9/14 (64%)
		PAM2	108..123	CDD:284542	10/13 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	61	1.000	Inparanoid score	I5392
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51398
OrthoDB	1	1.010	-	-		D1624094at2759
OrthoFinder	1	1.000	-	-		FOG0004724
OrthoInspector	1	1.000	-	-		otm41632
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3889
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.970