DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7091 and CG3036

DIOPT Version :9

Sequence 1:	NP_650243.2	Gene:	CG7091 / 41590	FlyBaseID:	FBgn0038099	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	486	Identity:	140/486 - (28%)
Similarity:	229/486 - (47%)	Gaps:	40/486 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 SVRLTYAICAFLATCLHAAMRNMLGMIILKMVMPRPEDALVVPAGLSRLTEGNVTSTGRCGSPRV 89
            |.|....:...|...|:.|:|..|.:.|:.||.|.      |.:.::....||.|:.....||..
  Fly    17 SCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPN------VTSAVNATLVGNSTAANSTASPDG 75

  Fly    90 VFNPQIQETQSGDLPWTRNQELTFPGVYYYGYVVSISLSGYLADRCSSKRLFIVSLIFEAVAYIL 154
            |   .:.|.:   .||...|.....|.:::||:::....|.||:....:|:|..|:::.::..::
  Fly    76 V---DVYEER---FPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLI 134

  Fly   155 LPAMAHSSFEAGVVDLVICGLLAGCGNPAMYKLFVTWAHPTERTALLSFAYSGLLMGSMLVYPVA 219
            .|..||.::...:|..|:.|.:.|...||::.:...|..|.||:..:|...:..| |:.:..|:.
  Fly   135 TPLAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASSL-GAAITMPIC 198

  Fly   220 SYL-SNFGWELSFYVVGGVGLSFGIACCFLVYDTVEQHPRISNEEVDYLRQGKSQLGQQRQPVVT 283
            .|| |..||...||:.|.|||.:.:|....||:|...|||||.||...:.:.......:::| ..
  Fly   199 GYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRP-SH 262

  Fly   284 IPWKSLLAAPPVYAFILTHMFHTYTFLVIVQLMPRFMREAMEFDLREVGFLSAAPYLGGICSKVM 348
            :||..||.:|.|:|.|:.|....:.|..:|..:|.||.:.:.||:::.|..|:.||||    |.:
  Fly   263 VPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLG----KYV 323

  Fly   349 CILGGSYVE---RRVGPDQNCVRRMLYGICSILTTSLIGVIIL-----ANCDDKILVLVMFAFMM 405
            ..:..||:.   |:.|.......|.|:...:::...|:.::.:     |.....|..|.:||...
  Fly   324 MAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTIFSLALFAHGA 388

  Fly   406 ATTDMGFSGYWPTLLYFAPSFAGLLSGLANGMAHLSGFLAPHLVAALVHTGSKDE----WNVVLM 466
            .|     :||....|..||:|.|.:.||||.::...|||:..:|.||.:   ||:    |.:|..
  Fly   389 VT-----AGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTY---KDQSFHSWQIVFW 445

  Fly   467 TLIVFNTMAMLVFAFCSSTNLQPW-DPRSRM 496
            .|......|.:|||...|..|||| :|..|:
  Fly   446 ILAATYISAAVVFAILGSGELQPWNNPPERV 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7091	NP_650243.2	2A0114euk	77..498	CDD:129972	127/434 (29%)
CG7091	NP_650243.2	MFS	115..482	CDD:119392	111/379 (29%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	139/484 (29%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	114/391 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970