DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and SCARF1

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_003684.2	Gene:	SCARF1 / 8578	HGNCID:	16820	Length:	830	Species:	Homo sapiens

Alignment Length:	370	Identity:	79/370 - (21%)
Similarity:	107/370 - (28%)	Gaps:	129/370 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 ICSK-NICLCRQGYYAR-----------------------NGKCFAELGEIAESTD----ECEY- 423
            :|.| .:|.|:.|::..                       :|:|....|......|    .||:
Human    68 VCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132

  Fly   424 -------EFDQLTKTCNCQKNYFYERDLRNCRKPIQYHLSCTSNSQCSPFGASYCHP-------- 473
                   ..|..|..|:|:..::..    .||:|.|.:.:.....|.:  ||..|.|
Human   133 CACGPHGRCDPATGVCHCEPGWWSS----TCRRPCQCNTAAARCEQAT--GACVCKPGWWGRRCS 191

  Fly   474 -----------EIPRRCTCEEYALYDAIKQLCEYKRG---------------LGAECESNDGCPV 512
                       :...||.|.........:|.||..||               .||.||.  .||.
Human   192 FRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCEL--PCPA 254

  Fly   513 -DHSVCSNRVCVCADNYFEKDDQCMRGIGADCSVEDDCIPENTECQEKDEEDQSRTCQ--CRKGY 574
             .|.|                 ||....|. |...:.|.|:...|:..:.......||  |..|
Human   255 GSHGV-----------------QCAHSCGR-CKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG- 300

  Fly   575 VHFKDECLKEAEELEDECVEDEQCKPLLASCN--SEGKCG--CNDEQHAKNGVCETKRELGESCT 635
             .|.:.|    |:....|...|.|:|....|.  ..|..|  |.|.       |.| ...||.|.
Human   301 -TFGESC----EQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDP-------CPT-GTFGEDCG 352

  Fly   636 KATECYVEKDPENVECRNSVCQCKLGY---SANA------NQNQC 671
            ......|:...:.|   ...|.|..||   |.||      :.|.|
Human   353 STCPTCVQGSCDTV---TGDCVCSAGYWGPSCNASCPAGFHGNNC 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	14/57 (25%)
		EB	613..665	CDD:279949	14/54 (26%)
SCARF1	NP_003684.2	CSRNP_N	<100..135	CDD:292638	6/34 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	516..539
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	581..688
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	715..830
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900