DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and dkk1a

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001268729.2	Gene:	dkk1a / 799377	ZFINID:	ZDB-GENE-090313-406	Length:	247	Species:	Danio rerio

Alignment Length:	221	Identity:	46/221 - (20%)
Similarity:	70/221 - (31%)	Gaps:	84/221 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CETEADCTADGTSCDFASGQCECSTFDTVLAENFTQCLATSLIGEKC-DDSVQCNLMPTGASCKA 96
            |..:::|:. |..|:.:.|                .||:.....::| .|.:.|    .|..|..
Zfish    68 CSADSECSI-GEFCNGSRG----------------VCLSCRKRRKRCARDGMCC----AGNRCIN 111

  Fly    97 GVCDCAD-------------------------GQNYLRGK-----CRP----LNGLGESCETDLD 127
            |||..||                         |||:...:     .:|    ..|.||:|....|
Zfish   112 GVCQLADAAAVGSADASPPGGNTDVSGVAVTRGQNFTHPRRTTVLSKPQQTQKGGEGETCLRSSD 176

  Fly   128 CYFGYDRASVSCQQNVCGCANGYYNRY-------GNICRRKSMEENDACVVNADCDELGAGVECV 185
            |..|           :| ||..:::|.       |.:|.|...:......:...|| .|:|:.|.
Zfish   177 CLEG-----------LC-CARHFWSRICKPVLTEGQVCTRHRRKGAHGLEIFQRCD-CGSGLTCR 228

  Fly   186 GLVCTYVDEITTTPGGETEETETTNP 211
            |.        ...||.|:....|..|
Zfish   229 GQ--------REKPGAESRNLHTCQP 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949	15/74 (20%)
		EB	101..155	CDD:279949	17/94 (18%)
		EB	570..624	CDD:279949
		EB	613..665	CDD:279949
dkk1a	NP_001268729.2	Dickkopf_N	68..115	CDD:282549	14/67 (21%)
dkk1a	NP_001268729.2	COLIPASE	167..236	CDD:305210	20/89 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900