Protein Alignment CG7381 and Pear1

DIOPT Version :9

• Sequence 1: NP_650242.1
• Gene: CG7381 / 41589
• FlyBaseID: FBgn0038098
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001027585.1
• Gene: Pear1 / 73182
• MGIID: 1920432
• Length: 1034
• Species: Mus musculus
• Alignment Length: 783
• Identity: 150/783 - (19%)
• Similarity: 221/783 - (28%)
• Gaps: 359/783 - (45%)

  Fly    10 LGVLCCAVLSPQGDGGVLAVFWP-CETEADCTADGTSCDFASGQCECSTFDTVLAENFTQCLATS 73
            :||: |::..|:|..|      | |..|..| .:|..||..:|||.|               |..
Mouse   253 MGVI-CSLPCPEGFHG------PNCTQECRC-HNGGLCDRFTGQCHC---------------APG 294

  Fly    74 LIGEKCDDSVQCNLMPTGASCKAGVCDCADGQNYLRGKCRPLNGLGESCETDLDCYFGY--DRAS 136
            .||::|.:  :|.:...|..| |..||||.|     .:|.|.||   :|.    |..|:  ||
Mouse   295 YIGDRCQE--ECPVGRFGQDC-AETCDCAPG-----ARCFPANG---ACL----CEHGFTGDR-- 342

  Fly   137 VSCQQNVCGCANGYYNRYGNICRRKSMEENDACVVNADCDELGAGVECVGLVCTYVDEITTTPGG 201
              |.:.:  |.:|   |||..|:       :.|
Mouse   343 --CTERL--CPDG---RYGLSCQ-------EPC-------------------------------- 361

  Fly   202 ETEETETTNPGSPEDDDSTTAEAITETADPEQETAFSSRRQLTKAFVHAPPPTHSDAAAQVSFAQ 266
                                      |.|||...:           .|   |.|.:.:.|..:|.
Mouse   362 --------------------------TCDPEHSLS-----------CH---PMHGECSCQPGWAG 386

  Fly   267 LTNGDTEPLISPRSHEIAVQTSIEKYELREVGRSVRNAATATTTTTATASTSTSSRRNSSRNQRH 331
            |...::.|
Mouse   387 LHCNESCP--------------------------------------------------------- 394

  Fly   332 AHGQRRRLPALFRFDDEDIKTYSTLGSSRDDDDADEKKYGSSCTDNGKTCSGLPHSIC--SKNIC 394
                                               :..:|..|.::   |..|...:|  ...:|
Mouse   395 -----------------------------------QDTHGPGCQEH---CLCLHGGLCLADSGLC 421

  Fly   395 LCRQGYYARNGKCFAEL------GEIAESTDECEYEF--DQLTKTCNCQKNYFYERDLRNCRKPI 451
            .|..||   .|...|.|      |....|...||...  ..:..||.|::.  ::|.  ||..|.
Mouse   422 RCAPGY---TGPHCANLCPPDTYGINCSSRCSCENAIACSPIDGTCICKEG--WQRG--NCSVPC 479

  Fly   452 ---QYHLSCTSNSQCSPFGASYCHPEIPRRCTCEEYALYDAIKQL-C---EYKRGLGA--ECESN 507
               .:..:|.::.||:..|.  |.|: ...|||.. ..:.|..|| |   ::..|..:  :|:.:
Mouse   480 PLGTWGFNCNASCQCAHDGV--CSPQ-TGACTCTP-GWHGAHCQLPCPKGQFGEGCASVCDCDHS 540

  Fly   508 DGCPVDHSVC--------------------------------------SNRVCVCADNYFEKDDQ 534
            |||...|..|                                      .|..||||..:  :...
Mouse   541 DGCDPVHGQCRCQAGWMGTRCHLPCPEGFWGANCSNTCTCKNGGTCVSENGNCVCAPGF--RGPS 603

  Fly   535 CMR-----GIGADCSVEDDCIPENTECQEKDEEDQSRTCQCRKGYVHFKDECLKEAEELEDECVE 594
            |.|     ..|..| |:..|...::.|...|     .||.|..|:.             ..:|
Mouse   604 CQRPCPPGRYGKRC-VQCKCNNNHSSCHPSD-----GTCSCLAGWT-------------GPDC-- 647

  Fly   595 DEQCKP--------LLASCNSEGKCGCNDEQHAKNGVCE-TKRELGESCTKATECYVEKDPE--- 647
            .|.|.|        .|..|:..|.|      |.::|.|. |....|.:|       :|..|.
Mouse   648 SEACPPGHWGLKCSQLCQCHHGGTC------HPQDGSCICTPGWTGPNC-------LEGCPPRMF 699

  Fly   648 NVECRNSVCQCKLGYSANANQNQCIRVMPNKKNSSGRPSALKIITFM------------LIGSAF 700
            .|.| :.:|||.||...:.....|: ..|....:..:..:.:..|.|            :||.|.
Mouse   700 GVNC-SQLCQCDLGEMCHPETGACV-CPPGHSGADCKMGSQESFTIMPTSPVTHNSLGAVIGIAV 762

  Fly   701 LIT 703
            |.|
Mouse   763 LGT 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949	13/43 (30%)
		EB	101..155	CDD:279949	16/55 (29%)
		EB	570..624	CDD:279949	12/61 (20%)
		EB	613..665	CDD:279949	15/55 (27%)
Pear1	NP_001027585.1	EMI	25..93	CDD:284877
		EGF_CA	535..580	CDD:304395	6/44 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	823..883
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	925..1034

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900