DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and tnfaip6

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001035333.2	Gene:	tnfaip6 / 678516	ZFINID:	ZDB-GENE-060421-2654	Length:	271	Species:	Danio rerio

Alignment Length:	209	Identity:	42/209 - (20%)
Similarity:	68/209 - (32%)	Gaps:	80/209 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CDFASGQCECSTFDTVLAE---NFTQCLATSLIGEKCDDSVQCNLMPTGASC---KAGVCDCADG 104
            |:|..|  ..:|||.:.|.   .|..|.|    |......|...::..|::|   |.|:.|
Zfish    68 CNFEGG--TLATFDQLEAARQIGFHVCAA----GWLDKGRVGYPIVKAGSNCGFGKVGIID---- 122

  Fly   105 QNYLRGKCRPLNGLGESCETDLDCYFGYDRASVSC---------------------QQNVCGCAN 148
            ..|         .|.:|...|:.|   |:..:..|                     .:.:|
Zfish   123 YGY---------RLNKSERWDVYC---YNPVAKECGGVHTDPEKVLVSPGYPDEYQDEQIC---- 171

  Fly   149 GYYN---RYGNICRRK----SMEENDACV----------------VNADC-DELGAGVECVGLVC 189
             |::   |:|:..|..    .:||:..|:                |...| |:|.......|.|.
Zfish   172 -YWHIRVRFGHRIRLHFLDFDIEEDTDCLSDHLEIYDSYDDVSGFVGRYCGDQLPDDFISTGNVM 235

  Fly   190 T--YVDEITTTPGG 201
            |  ::.:.:.|.||
Zfish   236 TLKFLSDSSVTAGG 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949	10/46 (22%)
		EB	101..155	CDD:279949	10/77 (13%)
		EB	570..624	CDD:279949
		EB	613..665	CDD:279949
tnfaip6	NP_001035333.2	Link_domain_TSG_6_like	46..138	CDD:239592	22/91 (24%)
tnfaip6	NP_001035333.2	CUB	145..254	CDD:278839	19/110 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900