DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7381 and Esm1

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_072126.1	Gene:	Esm1 / 64536	RGDID:	71013	Length:	184	Species:	Rattus norvegicus

Alignment Length:	182	Identity:	39/182 - (21%)
Similarity:	58/182 - (31%)	Gaps:	64/182 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LAVFWPCETEADCT--ADGTSCDFASGQC------ECSTFDTVLAENFTQCLAT--SLIGEKCDD 81
            |.:.|..:...||.  .|.|.|. :|.:|      :|.......|.....|..|  .:.|.||..
  Rat    16 LGMAWSAKYAVDCPEHCDNTECR-SSLRCKRTVLDDCGCCQVCAAGPGETCYRTVSGMDGVKCGP 79

  Fly    82 SVQCNL----------------MPTG---------ASCKAGVCDCADGQNYLRGKCRPLNGLGES 121
            .::|:.                .|.|         .:|::|:||      .:.|:|
  Rat    80 GLKCHFYSEEDDFGDEFGVCKDCPYGTFGMDCKETCNCQSGICD------RVTGRC--------- 129

  Fly   122 CETDLDC-YFGYDRAS----VSCQQNVCGCANGYYNRYGNICRRKSMEENDA 168
                ||. :|.|..|.    .|..|.....|:|    .||..|.:..:.|.|
  Rat   130 ----LDFPFFQYAAAKSPSRTSASQTERDAASG----DGNAVREEIGDRNAA 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949	13/70 (19%)
		EB	101..155	CDD:279949	11/58 (19%)
		EB	570..624	CDD:279949
		EB	613..665	CDD:279949
Esm1	NP_072126.1	IGFBP	28..83	CDD:395164	13/55 (24%)
Esm1	NP_072126.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..184		9/33 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900