DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7381 and Dkk2

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	XP_006501881.1	Gene:	Dkk2 / 56811	MGIID:	1890663	Length:	272	Species:	Mus musculus

Alignment Length:	335	Identity:	67/335 - (20%)
Similarity:	105/335 - (31%)	Gaps:	121/335 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 STLGSSRDDDDADEKKYGSSCTDNGKTCSGLPHSICSKNICLCRQGYYARNGKCFAELGEIAEST 418
            |.|||||...::.:...|      |:|.:...:.....|..|...|  ::.||...::|...:.|
Mouse    26 SQLGSSRAKLNSIKSSLG------GETPAQSANRSAGMNQGLAFGG--SKKGKSLGQVGNPPKHT 82

  Fly   419 DECEYEFDQLTKTCNCQKNYFYERDLRNCRKPIQYHLSCTSNSQCSPFGASYCHPEIPRRCTCEE 483
                           .|....|               .|:|:.:|..  ..|||........|
Mouse    83 ---------------LQPGEAY---------------PCSSDKECEV--GRYCHSPHQGSSAC-- 113

  Fly   484 YALYDAIKQLCEYKRGLGAECESNDG--CPVDHSVCSNRVCVCADNYFEKDDQCMRGIGADCSVE 546
                    .||..|:   ..|. .||  ||  .:.|:|.:|:....                |:.
Mouse   114 --------MLCRRKK---KRCH-RDGMCCP--GTRCNNGICIPVTE----------------SIL 148

  Fly   547 DDCIP--ENTECQEKDEEDQSR-------------TCQCRKGYVHFKDECLKEAEELEDECVE-- 594
            ...||  :.|..::::....|.             .....||  |..|.||:.::.::..|..
Mouse   149 TPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHSKMPHIKG--HEGDPCLRSSDCIDGFCCARH 211

  Fly   595 --DEQCKPLLASCNSEGKCGCNDEQHAKNGVCETKRELGE---------SCTKATECYVEKDPE- 647
              .:.|||:|    .:|:            ||..:|:.|.         .|.|...|.|.||..
Mouse   212 FWTKICKPVL----HQGE------------VCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDATY 260

  Fly   648 NVECRNSVCQ 657
            :.:.|..|||
Mouse   261 SSKARLHVCQ 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	12/57 (21%)
		EB	613..665	CDD:279949	14/55 (25%)
Dkk2	XP_006501881.1	Dickkopf_N	91..141	CDD:368068	17/67 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900