DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and ccbe1

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001157395.1	Gene:	ccbe1 / 555629	ZFINID:	ZDB-GENE-090506-7	Length:	401	Species:	Danio rerio

Alignment Length:	225	Identity:	56/225 - (24%)
Similarity:	79/225 - (35%)	Gaps:	56/225 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   491 KQLCE-YKRGLGAECESNDGCPVDHSVCSNRVC--VCADNYFEKDDQCMRGIGAD---------- 542
            |:.|| :|..|| :|     .|.|:.||:...|  .|.|::......|..|...|
Zfish    64 KKCCEGFKFVLG-QC-----IPEDYDVCAGAPCEQQCTDHFGRVVCTCYDGYRYDRERHRNREKP 122

  Fly   543 -CSVEDDCIPEN-TECQEK-DEEDQSRTCQCRKGYVHFKDECLKEAEELEDE---CVEDEQCKPL 601
             |...|:|...| |.|.:. .....|..|.|..|:.            |||:   |.:.|:. ||
Zfish   123 YCLDIDECANNNETVCSQMCVNTPGSYRCDCHSGFY------------LEDDGKTCTKGERA-PL 174

  Fly   602 LASCNS---EGKCG--CNDEQHAKNGVCETKRELGESCTKATECYVEKDPEN---VECRNSVCQC 658
            ....::   ||.|.  |.|....|..|.:.|::: ...:..||  :.|...|   :...||....
Zfish   175 FEKSDNVMKEGTCSATCEDFHQMKMTVLQLKQKM-SLLSSNTE--INKQMTNEKMMMTTNSFLPG 236

  Fly   659 KLGYSANANQNQCIRVMPNKKNSSGRPSAL 688
            ..|....|.       .|..|.|||.|..:
Zfish   237 PPGPPGPAG-------TPGAKGSSGSPGQM 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	15/61 (25%)
		EB	613..665	CDD:279949	12/54 (22%)
ccbe1	NP_001157395.1	FXa_inhibition	130..166	CDD:291342	11/47 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	229..321		10/38 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..401
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900