DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7381 and Scarf1

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001004157.2	Gene:	Scarf1 / 380713	MGIID:	2449455	Length:	820	Species:	Mus musculus

Alignment Length:	408	Identity:	94/408 - (23%)
Similarity:	135/408 - (33%)	Gaps:	94/408 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   352 TYSTLGSSRDDDDADEKKYGSS----------------CTDNGKTCSG----LPHSICSK-NICL 395
            |..|.||:.|.......| |||                ||.  ..|.|    ....:|.| .:|.
Mouse    18 TQGTQGSTLDPAGQHVCK-GSSPSELQCCPGWRQKDQECTI--PICEGPDACRKEEVCVKPGLCR 79

  Fly   396 CRQGYYAR--NGKCFAEL-GEIAESTDEC--EYEFDQLTKTCNCQKNYFYERDLRNCRKPIQYHL 455
            |:.|::..  :.:|..:. |.....|..|  ..:.:..|..|.||.||:.    |.|..|    .
Mouse    80 CKPGFFGAQCSSRCPGQYWGHDCRETCPCHPRGQCEPATGDCQCQPNYWG----RLCEFP----C 136

  Fly   456 SCTSNSQCSPFGASYCH-------PEIPRRCTCEEYALYDAIKQLCEYKRG-LGAECESNDGCPV 512
            :|..:.||.| ....||       |...|.|.|...:..|.....|....| .|..|..:..|..
Mouse   137 TCGPHGQCDP-KTGLCHCDPGWWSPTCRRPCQCNPASRCDQATGTCVCPPGWWGRRCSFSCNCHT 200

  Fly   513 DHSVCSNRVCVCADNYF----EKDDQCMRGIGADCSVED---DCIP--ENTECQEKDEEDQSRTC 568
            ...:..:..|||...::    .:..||:||   .|||..   .|.|  ....|:          .
Mouse   201 SPCMQDSGRCVCLPGWWGPECSRKCQCVRG---QCSVTSGHCSCPPGFHGIRCE----------L 252

  Fly   569 QCRKGYVHFKDECLKEAEELEDECVEDEQCKPLLASCNS--EGKCGCNDEQHAKNGVCETKRELG 631
            .|..|  |:..:|    :|....|..:..|.|:..:|.|  .|..|...:|....|.      .|
Mouse   253 PCNPG--HYGAQC----KESCGHCELNATCSPVTGNCESCKPGWNGTQCKQPCPAGT------FG 305

  Fly   632 ESCT-KATECYVEKDPENVECRNSVCQ-CKLGYSANANQNQCIRVMPNKKNSSGRPSALKIITFM 694
            |.|| :...|.:   .|..:.....|| |..|:..:..:|.|......|..||..|:..:
Mouse   306 ERCTGQCPRCRL---GEPCQAETGHCQHCDPGWLGHRCENPCPLGTFGKGCSSTCPACAQ----- 362

  Fly   695 LIGSAFLITSAAIKQAYY 712
              |:...:|...:..|.|
Mouse   363 --GTCDAVTGECVCSAGY 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	14/55 (25%)
		EB	613..665	CDD:279949	12/53 (23%)
Scarf1	NP_001004157.2	PHA03247	<541..781	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	549..685
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	715..820
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900