Protein Alignment CG7381 and PEAR1

DIOPT Version :9

• Sequence 1: NP_650242.1
• Gene: CG7381 / 41589
• FlyBaseID: FBgn0038098
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: XP_016856723.1
• Gene: PEAR1 / 375033
• HGNCID: 33631
• Length: 1125
• Species: Homo sapiens
• Alignment Length: 650
• Identity: 135/650 - (20%)
• Similarity: 206/650 - (31%)
• Gaps: 211/650 - (32%)

  Fly     6 WFLTLGVLCCAVLSPQGDGGVLAVFWP-CETEADCTADGTSCDFASGQCECSTFDTVLAENFTQC 69
            |..|:    |::..|:|..|      | |..|..| .:|..||..:|||.|       |..:|
Human   342 WMGTI----CSLPCPEGFHG------PNCSQECRC-HNGGLCDRFTGQCRC-------APGYT-- 386

  Fly    70 LATSLIGEKCDDSVQCNLMPTGASCKAGVCDCADGQNYLRGKCRPLNG--------LGESCETDL 126
                  |::|.:  :|.:...|..| |..||||..     .:|.|.||        .|:.| ||.
Human   387 ------GDRCRE--ECPVGRFGQDC-AETCDCAPD-----ARCFPANGACLCEHGFTGDRC-TDR 436

  Fly   127 DCYFGYDRASVSCQQNVCGCANGYYNRYGNICRRKSMEENDAC-VVNADCDEL--GAGVECVGLV 188
            .|..|:  ..:|||. .|.|               ..|.:.:| .:|.:|..|  .||:.|
Human   437 LCPDGF--YGLSCQA-PCTC---------------DREHSLSCHPMNGECSCLPGWAGLHC---- 479

  Fly   189 CTYVDEITTTPGGETEETETTNPGSPEDDDSTTAEAITETADPEQETAFSSRRQLTKAFVHAPPP 253
                        .|:...:|..||..|                                 |....
Human   480 ------------NESCPQDTHGPGCQE---------------------------------HCLCL 499

  Fly   254 THSDAAAQVSFAQLTNGDTEP----LISPRSHEIAVQTSIEKYELREVGRSVRNAATATTTTTAT 314
            ......|.....|...|.|.|    |..|.::.:......          |..||...:......
Human   500 HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARC----------SCENAIACSPIDGEC 554

  Fly   315 ASTSTSSRRNSSRNQRHAHGQRRRLPALFRFDDEDIKTYSTLGSSRDDDDADEKKYGSSCTDNGK 379
            .......|.|.|            :|                        .....:|.||   ..
Human   555 VCKEGWQRGNCS------------VP------------------------CPPGTWGFSC---NA 580

  Fly   380 TCSGLPHSICS--KNICLCRQGYYARNGKCFAELGEIAE---STDECEYE--FDQLTKTCNCQKN 437
            :|.....::||  ...|.|..|::..:.:.....|:..|   |..:|::.  .|.:...|.||..
Human   581 SCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAG 645

  Fly   438 YFYERDLRNCRKPIQYHLSCTSNSQCSPFGASYCHPEIPRRCTCEEYALYDAIKQLCE---Y-KR 498
            :...|...:|.:.: :.::|::...|...|.  |.|| ...|.|.......:.::.|:   | ||
Human   646 WMGARCHLSCPEGL-WGVNCSNTCTCKNGGT--CLPE-NGNCVCAPGFRGPSCQRSCQPGRYGKR 706

  Fly   499 GLGAECESNDGCPVDHSVC--SNRVCVCADNYFEKDDQCMRGIGADCSVEDDCIPENTECQEKDE 561
            .:..:|       .:||.|  ||..|.|...:          .|.|||  ..|.|.:.      .
Human   707 CVPCKC-------ANHSFCHPSNGTCYCLAGW----------TGPDCS--QPCPPGHW------G 746

  Fly   562 EDQSRTCQCRK-GYVHFKD-ECLKEAEELEDECVEDEQCKPLLASCNSEGKCGCNDEQHAKNGVC 624
            |:.::||||.. |..|.:| .|:.........|:|........|:|:...:||..::.|.:.|.|
Human   747 ENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGAC 811

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949	10/43 (23%)
		EB	101..155	CDD:279949	17/61 (28%)
		EB	570..624	CDD:279949	13/55 (24%)
		EB	613..665	CDD:279949	2/11 (18%)
PEAR1	XP_016856723.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910