DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and Ccbe1

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_848908.1	Gene:	Ccbe1 / 320924	MGIID:	2445053	Length:	408	Species:	Mus musculus

Alignment Length:	281	Identity:	62/281 - (22%)
Similarity:	100/281 - (35%)	Gaps:	95/281 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 DDDDADEKKYGSSCTDNGKTCSGLPHSICSKN-----ICL---CRQGYYARNGKCFAELGEI--- 414
            :.:|.|.:    .|::|..|.:..|   |.|:     .|.   |.:||....|:|..|..:|
Mouse    39 EPEDRDRE----VCSENKITTTKYP---CLKSSGELTTCFRKKCCKGYKFVLGQCIPEDYDICAQ 96

  Fly   415 AESTDECEYEFDQLTKTCNCQKNYFYERDLRNCRKPIQYHLSCTSNSQCSPFGASYC-HPEIPRR 478
            |....:|...|.::  .|.|...|.|:|: |:.::...|   |....:|:....:.| |
Mouse    97 APCEQQCTDNFGRV--LCTCYPGYRYDRE-RHQKRERPY---CLDIDECATSNTTLCAH------ 149

  Fly   479 CTCEEYALYDAIKQLCEYKRGLGAECESNDGCPVDHSVCSNRV----CVCADNYFEKDD--QCMR 537
                                                 :|.|.:    |.|.:.|..:||  .|.|
Mouse   150 -------------------------------------ICINTMGSYHCECREGYILEDDGRTCTR 177

  Fly   538 GIGADCSVEDDCIPENTECQEKDE-EDQSRTCQCRKGYVHFKDECLKEAEELEDECVEDEQCKPL 601
            |         |..|.:|..:||.| |.::.|| |.        .| ||..:::...::.:|...|
Mouse   178 G---------DKYPNDTGHEEKSENEVKAGTC-CA--------TC-KEFSQMKQTVLQLKQKMAL 223

  Fly   602 LASCNSE-GKCGCNDEQHAKN 621
            |.:..:| ||....|:..|.|
Mouse   224 LPNNAAELGKYVNGDKVLASN 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	13/53 (25%)
		EB	613..665	CDD:279949	3/9 (33%)
Ccbe1	NP_848908.1	EGF_CA	135..176	CDD:214542	10/83 (12%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..335
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	361..408
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900