DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and dkk1b

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_571078.1	Gene:	dkk1b / 30197	ZFINID:	ZDB-GENE-990708-5	Length:	241	Species:	Danio rerio

Alignment Length:	215	Identity:	48/215 - (22%)
Similarity:	82/215 - (38%)	Gaps:	51/215 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   473 PEIPRRCTCEEYALYDAIKQLCEYKRGLGAECES------NDG--CPVDHSVCSNRVCVCADNYF 529
            |:.|..|..:|..   ..::.|...||:..:|:.      .|.  ||.:|  |||.||:
Zfish    63 PQQPLICESDEEC---GGEEFCFQSRGVCLQCKKRRKRCIRDAMCCPGNH--CSNGVCI------ 116

  Fly   530 EKDDQCMRGIGAD--CSVEDDCIPENTECQEKDEEDQSRTCQCRKGYVHFKDECLKEAEELEDEC 592
            ..|...::.:|.:  .|:..:   .:|....|.....|...|..||..  .:.||:.::..|..|
Zfish   117 PNDPDIIQQLGMEEFVSIAHE---NSTALMPKVSTQGSPQNQMLKGLE--GENCLRSSDCAETLC 176

  Fly   593 VE----DEQCKPLLASCNSEGKCGCNDEQHAKNGVCETKRELGESCTKATECYVEKDPENVECRN 653
            ..    .:.|||:|    .||:.....::...:|:     |:.:.|    :|     .|.:.||.
Zfish   177 CARHFWSKICKPVL----KEGQVCTKHKRKGTHGL-----EIFQRC----DC-----GEGLSCRT 223

  Fly   654 SVCQCKLGYSANANQNQCIR 673
               |...|..|:.:.:.|.|
Zfish   224 ---QRGDGGKASRSLHTCQR 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	13/57 (23%)
		EB	613..665	CDD:279949	9/51 (18%)
dkk1b	NP_571078.1	Dickkopf_N	69..116	CDD:282549	14/51 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900