DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and Dkk1

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001099820.1	Gene:	Dkk1 / 293897	RGDID:	1307313	Length:	270	Species:	Rattus norvegicus

Alignment Length:	192	Identity:	42/192 - (21%)
Similarity:	61/192 - (31%)	Gaps:	59/192 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 WPCETEADCTADGTSCDFASGQCECSTFDTVLAENFTQCLATSLIGEKCDDSVQCNLMPTGASCK 95
            :||..:.:|..|        ..|...:...........|||.....::|.....|  .| |..||
  Rat    84 YPCAEDEECGTD--------EYCSSPSRGAAGVGGVQICLACRKRRKRCMRHAMC--CP-GNYCK 137

  Fly    96 AGVCDCADGQNYLRGKCRPLNGLGESCETDLDCYFGYDR--------------------ASVSCQ 140
            .|:|..:|..:..||:..  .|:.|:...|.....||.|                    .|..|.
  Rat   138 NGICMPSDHSHLPRGEIE--EGIIENLGNDHGAGDGYPRRTTLTSKIYHTKGQEGSVCLRSSDCA 200

  Fly   141 QNVCGCANGYYNRY-------GNIC---RRK---SMEENDACVVNADCDELGAGVECVGLVC 189
            ..:| ||..::::.       |.:|   |||   .:|....|.    |.|        ||.|
  Rat   201 TGLC-CARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCY----CGE--------GLAC 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949	14/43 (33%)
		EB	101..155	CDD:279949	14/80 (18%)
		EB	570..624	CDD:279949
		EB	613..665	CDD:279949
Dkk1	NP_001099820.1	Dickkopf_N	86..142	CDD:398399	14/66 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900