DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and Scarf2

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	XP_038944006.1	Gene:	Scarf2 / 287949	RGDID:	1306013	Length:	838	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	97/448 - (21%)
Similarity:	135/448 - (30%)	Gaps:	155/448 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 KKYGSSCTDNGKTCSGLPHSICSKN-------ICLCRQGYYARN--GKCFAEL------------ 411
            ::.|..|  ....|.|  :|.||:|       .|.||.||:..|  .||..:.
  Rat    61 RQLGDEC--GIAVCEG--NSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKERCSCH 121

  Fly   412 --GEIAESTDECEYEF----DQLTKTCNCQKNYFYERDLRNCR-KPIQYHLSCTS------NSQC 463
              |:..:.|.:|....    .:....|.||....:.|. ..|| :|..:...|.|      .|:|
  Rat   122 PHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRS-GACRCEPGWWGAQCASACYCSATSRC 185

  Fly   464 SP-FGASYCHP-----EIPRRCTCEEYALYDAIKQLCEYKRG--------LGAECESNDGC---- 510
            .| .||..||.     ....:|:|.        ...||.:.|        .||.|:....|
  Rat   186 DPQTGACLCHAGWWGRSCNNQCSCN--------SSPCEQQSGRCQCRERTFGARCDRYCQCFRGR 242

  Fly   511 --PVDHSVCSNRVCVCADNYFEK--DDQCMRGI-GADCS--------------VEDDCIP----- 551
              |||.:      |.|...|..|  .:.|..|. |..|.              ||..|:.
  Rat   243 CHPVDGT------CACDPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVVEGRCLTCEPGW 301

  Fly   552 ENTECQEK------DEEDQSRTCQCRKGYV--HFKDECLK-EAEELEDEC-------VEDEQCKP 600
            ..|:|.:.      .|....|...||.|:.  |...:|.. .|..:.|.|       ...|.|..
  Rat   302 NGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTHCNAGWIGDRCETKCSNGTYGEDCAF 366

  Fly   601 LLASCNS------EGKCGCNDEQHAK--NGVCETKRELGESCTKATECYVEK-DPENVEC----- 651
            :.:.|.|      .|:|.|:...|..  |..|..... |..|.:|..|:.|. ||....|
  Rat   367 VCSDCGSGHCDFQSGRCLCSPGVHGPHCNVTCPAGLH-GVDCAQACSCHEESCDPVTGACHLETN 430

  Fly   652 -RNSV---------------------CQCKLGYSANANQNQCIRVMPNKKNSSGRPSA 687
             |..|                     |.|:       .::...|..|.::.:.||..|
  Rat   431 QRKGVMGAGALLTLLLGLLLSLLGCCCACR-------GKDSARRPRPRRELTLGRKKA 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	17/71 (24%)
		EB	613..665	CDD:279949	16/81 (20%)
Scarf2	XP_038944006.1	exchanger_TraA	<74..431	CDD:411343	85/374 (23%)
Scarf2	XP_038944006.1	PHA03247	<683..837	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900