DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7381 and Dkk4

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_663567.1	Gene:	Dkk4 / 234130	MGIID:	2385299	Length:	221	Species:	Mus musculus

Alignment Length:	210	Identity:	43/210 - (20%)
Similarity:	73/210 - (34%)	Gaps:	72/210 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   457 CTSNSQCSPFGASYC---HPEIPRRCTCEEYALYDAIKQLCEYKRGLGAECESNDGCPVDHSVCS 518
            |.|:..||.  ..:|   |.|.....||..      :::.|:    ..|.|     ||  .:||.
Mouse    41 CASDRDCSE--GKFCLAFHDERSFCATCRR------VRRRCQ----RSAVC-----CP--GTVCV 86

  Fly   519 NRVCVCADNYFEKDDQCMRGIGADCSVEDDCIPENT--------ECQEKDEEDQSRTCQCRKGYV 575
            |.||...::.....|:...|       :|....|.|        ..|.|....:|::.:.::|
Mouse    87 NDVCTAVEDTRPVMDRNTDG-------QDGAYAEGTTKWPAEENRPQGKPSTKKSQSSKGQEG-- 142

  Fly   576 HFKDECLKEAEELEDECVE----DEQCKPLLAS---CNSEG------------KCGC-------- 613
               :.||:.::.....|..    .:.|||:|..   |:..|            :|.|
Mouse   143 ---ESCLRTSDCGPGLCCARHFWTKICKPVLREGQVCSRRGHKDTAQAPEIFQRCDCGPGLTCRS 204

  Fly   614 ---NDEQHAKNGVCE 625
               ::.||::..||:
Mouse   205 QVTSNRQHSRLRVCQ 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	14/83 (17%)
		EB	613..665	CDD:279949	5/24 (21%)
Dkk4	NP_663567.1	Dickkopf_N	41..91	CDD:368068	18/68 (26%)
		DKK-type Cys-1	41..90		17/67 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..143		9/53 (17%)
		DKK-type Cys-2	145..218		13/72 (18%)
		Prokineticin	<145..202	CDD:148298	11/56 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900