DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and Tnfaip6

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_033424.1	Gene:	Tnfaip6 / 21930	MGIID:	1195266	Length:	275	Species:	Mus musculus

Alignment Length:	230	Identity:	46/230 - (20%)
Similarity:	72/230 - (31%)	Gaps:	80/230 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CDFASGQCECSTFDTVLAE---NFTQCLATSLIGEKCDDSVQCNLMPTGASC---KAGVCDCADG 104
            |:|..|:  .:|:..:.|.   .|..|.|    |......|...::..|.:|   |.|:.|..
Mouse    58 CEFEGGR--LATYKQLEAARKIGFHVCAA----GWMAKGRVGYPIVKPGPNCGFGKTGIIDYG-- 114

  Fly   105 QNYLRGKCRPLNGLGESCETDLDCYFGYDRASVSCQQNVCG----------CANGYYNRY--GNI 157
               :|        |..|...|..||..:.:.        ||          .:.|:.|.|  ..:
Mouse   115 ---IR--------LNRSERWDAYCYNPHAKE--------CGGVFTDPKRIFKSPGFPNEYDDNQV 160

  Fly   158 C----RRK------------SMEENDACV----------------VNADC-DELGAGVECVGLVC 189
            |    |.|            .:|.:..|:                |...| |||...:...|.|.
Mouse   161 CYWHIRLKYGQRIHLSFLDFDLEHDPGCLADYVEIYDSYDDVHGFVGRYCGDELPEDIISTGNVM 225

  Fly   190 T--YVDEITTTPGGETEETETTNPGSPEDDDSTTA 222
            |  ::.:.:.|.||...:..|.:|.|.......|:
Mouse   226 TLKFLSDASVTAGGFQIKYVTVDPASKSSQAKNTS 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949	10/46 (22%)
		EB	101..155	CDD:279949	11/65 (17%)
		EB	570..624	CDD:279949
		EB	613..665	CDD:279949
Tnfaip6	NP_033424.1	Link_domain_TSG_6_like	36..128	CDD:239592	19/88 (22%)
		CUB	135..244	CDD:278839	21/108 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	253..275		1/8 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900