DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and F56B3.2

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_499983.2	Gene:	F56B3.2 / 176902	WormBaseID:	WBGene00018928	Length:	432	Species:	Caenorhabditis elegans

Alignment Length:	403	Identity:	84/403 - (20%)
Similarity:	136/403 - (33%)	Gaps:	116/403 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 DDDADEKKYGSSC---------------TDNGK--TCSGLPHSICSKNICLCRQGYYARNGKC-F 408
            |.:.|.:..||.|               .:.|:  .|:.||..|.::....||:..:.|||:| .
Worm    39 DINGDCENKGSICLRGKCRCHPHYTETRDEKGRLPKCAPLPAKIGARCSSKCREPLFCRNGECQC 103

  Fly   409 AELGEIAESTDECEYEFDQLTKT---CNCQKNYFYERDLRNCRKPIQYHLSCTSNSQCSPFGASY 470
            .:.|....|..||      :|.:   ..|.::|       :|..|    .|...||||.....:.
Worm   104 VQRGTTRVSNGEC------ITTSRVGDRCSRHY-------DCTSP----FSACVNSQCVCITGTI 151

  Fly   471 CHPEIPRRCTCEEYALYDAIK-QLCEYKR--GLGAECESN-DGCPVDHSVCSNRVCVCADNYFEK 531
               ::..||.......:..:. |.|..|.  .|.....|| |.||:      .:||:.|.
Worm   152 ---QMGSRCVAAANCPFGKLPGQSCVRKSDPSLAFNIPSNQDNCPM------GQVCITAG----- 202

  Fly   532 DDQCMRGIGADCSVEDDCIPENTECQEKDEEDQSRT----CQCRKGYVHF-KDECLKEAEELEDE 591
            :.|    :|..|.|   ..|.||....:...|....    |.....|.:| .|....:|......
Worm   203 ESQ----VGHCCPV---ICPLNTTTDTRYSCDPDAAPALKCPSDSHYCYFLSDGSFSQAACCRRP 260

  Fly   592 C--------VEDEQCKP---LLASCNSEGKCGCNDEQHAKNGVCETKREL--------------G 631
            |        ..|..|.|   |.::|.|..:||..:......|.|:.::..              .
Worm   261 CNAMAPNALYVDYHCMPRGQLNSACTSNAQCGGGEGMECMKGQCQCQQNFHPAVDVLTNPLKNPS 325

  Fly   632 ESCTKATE-------------------CYVEKD-PENVECRNSVCQCKLGYSANANQNQCIRV-M 675
            :||::..|                   |:::|. |:|..|....|.|:.|::  |...:|:.: .
Worm   326 QSCSRDCESENLSKDTSCMKAVPLNSLCFIQKQCPQNSGCYRGRCMCRCGFA--AKNGKCVEIPA 388

  Fly   676 PNKKNSSGRPSAL 688
            |....|:..|:.:
Worm   389 PPTTTSAPAPAII 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	14/65 (22%)
		EB	613..665	CDD:279949	13/85 (15%)
F56B3.2	NP_499983.2	EB	111..157	CDD:279949	13/65 (20%)
		EB	266..312	CDD:279949	10/45 (22%)
		EB	332..383	CDD:279949	10/52 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900