DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7381 and AgaP_AGAP010789

DIOPT Version :9

Sequence 1:	NP_650242.1	Gene:	CG7381 / 41589	FlyBaseID:	FBgn0038098	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	XP_318519.4	Gene:	AgaP_AGAP010789 / 1278873	VectorBaseID:	AGAP010789	Length:	321	Species:	Anopheles gambiae

Alignment Length:	352	Identity:	88/352 - (25%)
Similarity:	131/352 - (37%)	Gaps:	104/352 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   408 FAELGEIAESTD-ECEYEFDQLTKTCNCQKNYFYERDLRNCRKPIQYHLSCTSNSQ------CSP 465
            :.:|.|:...|| :|| .|...|....|                |:.|..||..||      |.|
Mosquito     5 WTDLVELTCETDQDCE-PFRSATVNSTC----------------IEEHCRCTDLSQNGNATECRP 52

  Fly   466 F----------------GASYCHPEIPRRCTCEEYALYDAIKQLCEYKR-GLGAECESNDGCP-V 512
            .                ..|:|| |..|||.|::..|.....:.|.||. .||.|||:|:.|. .
Mosquito    53 LVNRVSNHIGGQCPCQVANSFCH-EQTRRCICKDGFLPSREDRKCVYKSVQLGGECENNEQCSNH 116

  Fly   513 DH-SVCSNRVCVCADNYFEKDDQC-----MRGIGADCSVEDDCI--PENTECQEKDEEDQSRTCQ 569
            || :.|..:||.|.:::...:..|     :..:...|:.:|:|.  ..|:.|       .:..|.
Mosquito   117 DHFADCREQVCQCQEHFVLHEGACRSIIAVANLKKPCAADDECANGTSNSVC-------HAGQCL 174

  Fly   570 CRKGYV--HFKDECLKEAEELEDECVEDEQCKPLLAS------CNSEGKCGCNDE---------- 616
            |...:|  .....||..| .|:..|.:..||   :||      |..| :|||:..
Mosquito   175 CGVDFVADATNSSCLAVA-ALDQPCTDTNQC---IASLGVGSICYRE-RCGCDSNHFQFPLPVTN 234

  Fly   617 ----QHAKNGVCETKRELGESCTKATECY---VEKDPENVECRNSVCQCKLGYSANAN----QNQ 670
                |.|...|||.|...|:||.....||   |....:::||..:.|.|..|:....|    .|.
Mosquito   235 ATTGQQAVQNVCERKIVHGDSCNDDQNCYQFHVGPHEQSMECYMNACVCLTGFVEKNNICYKANT 299

  Fly   671 CIRVMPNKKNSSGRPSALKIITFMLIG 697
            .:.::|:            .:.|::||
Mosquito   300 GVIIVPS------------TLLFVVIG 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	18/75 (24%)
		EB	613..665	CDD:279949	18/68 (26%)
AgaP_AGAP010789	XP_318519.4	EB	<98..140	CDD:279949	15/41 (37%)
AgaP_AGAP010789	XP_318519.4	EB	236..294	CDD:279949	18/57 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820