Protein Alignment CG7381 and adgre2

DIOPT Version :9

• Sequence 1: NP_650242.1
• Gene: CG7381 / 41589
• FlyBaseID: FBgn0038098
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: XP_002941921.2
• Gene: adgre2 / 100485797
• XenbaseID: XB-GENE-6046733
• Length: 803
• Species: Xenopus tropicalis
• Alignment Length: 555
• Identity: 114/555 - (20%)
• Similarity: 170/555 - (30%)
• Gaps: 186/555 - (33%)

  Fly   211 PGSPEDDDSTTAEAITETADPEQETAFSSRRQLTKAFVHAPPPTHSDAAAQVSFAQLTNGDTEPL 275
            |..||...||....|   ..|.....|:...|...|..|...|  :...||.....|.:|
 Frog    36 PHQPEPGKSTVLSGI---RPPTPGLGFNRGAQPLTATEHGNQP--NSGVAQQGTGDLPHG----- 90

  Fly   276 ISPRSHEIAVQTSIEKYELREVGRSVRNAATATTTTTATASTSTSSRRNSSRNQRHAHGQRRRLP 340
                                .||......|......|:.....:||..||..:.....|
 Frog    91 --------------------TVGNPALKTAKPLGVQTSGGKADSSSSPNSVADVDECAG------ 129

  Fly   341 ALFRFDDEDIKTYS----TLGS------------SRDDDDADEKKYGSSCTDNGKTCSGL----P 385
                 .:.....||    |:||            ....:|.||.:...:        :||    |
 Frog   130 -----PEPPCGLYSNCTNTVGSYLCRCLRGFLRGPNGCEDVDECQLAEA--------TGLQACPP 181

  Fly   386 HSICSKNI----CLCRQGY-YARNG-------------KCFAELGEIAESTD-----ECEYEFDQ 427
            ||.|...:    |.|..|: :..:|             ||..|||.:..:|:     .|:..|.:
 Frog   182 HSSCRNTLGSFACSCDPGFVFGLDGKRCVDIDECAFEEKCRRELGNLCVNTEGSYRCRCQAGFRE 246

  Fly   428 LTKTC----NCQKNYFYERDLRNCRKPIQYHL-------------------------SCTSNSQC 463
            ..:.|    .|.:|......|..|...:..::                         .|.||:.|
 Frog   247 TGQACVDIDECAENPSLCSGLGVCENSLGSYVCGCQPGFRGNGTYCEDENECASGGHGCDSNAHC 311

  Fly   464 SPFGASYCHPEIPRRCTC------EEYALYDAIKQLCEYKRGLGAECESNDG-CPVDHSVCSNRV 521
            .....||.       |.|      :.::.:|.            .||..|:| ||  || |.|:.
 Frog   312 GNIIGSYF-------CQCYQGFNGDGHSCFDI------------DECSVNNGDCP--HS-CVNQA 354

  Fly   522 ----CVCADNYFEKDDQCMRGIGADCSVEDDCIPENTEC-QEKDEEDQSRTCQCRKGYVHFKDEC 581
                |.|...|..::|      ..:|:..|:|...|.|| |..:..|.|..|.||||:....|
 Frog   355 GSYRCQCRPGYLLQED------AKNCTDIDECETANGECAQICENTDGSYGCSCRKGFQLHVD-- 411

  Fly   582 LKEAEELEDECVEDEQCKPLLASCNSEGKCG--CNDEQHAKNGVCETKRELGE---SCTKATECY 641
            ||       :|::.::||      ...|.|.  ||:.:.....:|...:.|.:   :|...|.|.
 Frog   412 LK-------QCIDIDECK------IDNGGCAHTCNNTEGGFLCLCPPHQALAKDSRTCINITSCS 463

  Fly   642 VEKDPENVECRNS-----VCQCKLGYSANANQNQC 671
            ......:..|...     .|.|:.|:..::|...|
 Frog   464 TRNGGCDHVCSQKQEGGFECSCRAGWLLSSNGRTC 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7381	NP_650242.1	EB	68..112	CDD:279949
		EB	101..155	CDD:279949
		EB	570..624	CDD:279949	14/55 (25%)
		EB	613..665	CDD:279949	11/59 (19%)
adgre2	XP_002941921.2	EGF_CA	123..160	CDD:214542	6/47 (13%)
		cEGF	191..214	CDD:372248	4/22 (18%)
		EGF_CA	211..252	CDD:214542	8/40 (20%)
		EGF_CA	253..293	CDD:214542	4/39 (10%)
		EGF_3	298..333	CDD:372403	8/41 (20%)
		FXa_inhibition	339..374	CDD:373209	13/43 (30%)
		vWFA	<374..413	CDD:381780	15/40 (38%)
		FXa_inhibition	421..456	CDD:373209	8/40 (20%)
		FXa_inhibition	462..498	CDD:373209	6/35 (17%)
		vWFA	<495..539	CDD:381780	1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010