DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment grsm and LAP1

DIOPT Version :9

Sequence 1:	NP_731749.3	Gene:	grsm / 41587	FlyBaseID:	FBgn0040493	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001118375.1	Gene:	LAP1 / 816954	AraportID:	AT2G24200	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	488	Identity:	142/488 - (29%)
Similarity:	226/488 - (46%)	Gaps:	58/488 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 SHLESKLSPRVTEETFLNAVACLHPAPTDKVSLYLDVATVAALP-LKASRHNTASRAHAITRLVK 221
            :||...|:...:||.|           |.|..    .:||..|| |.:.|........:::..|.
plant    62 AHLSGLLAQVSSEEDF-----------TGKPG----QSTVLRLPGLGSKRIALIGLGQSVSSPVA 111

  Fly   222 NHVLNVSEESVVLVCERENLFASACAVVRAFPLYSRKTGNLLASSQPKLNLGC-GDGNANSGRNV 285
            .|.|.   |:|..|.:...  :::.|:|.|..:......:.:::....:.||. .||...|....
plant   112 FHSLG---EAVATVSKASQ--STSAAIVLASSVSDESKLSSVSALASGIVLGLFEDGRYKSESKK 171

  Fly   286 VNVEFVLINKDGCIESEPLTDDELNCLNETTRAIRMTARIVDMPCNEMNVDHFIQEVEDVGREL- 349
            .:::.|.|...|   :....:.:|....:.:..:.....:::.|.|.:......:|...|....
plant   172 PSLKAVDIIGFG---TGAEVEKKLKYAEDVSYGVIFGRELINSPANVLTPAVLAEEAAKVASTYS 233

  Fly   350 -CITPKVIRGEELLEQGFGGIYGVGKAAAVPPALVVLSHE-PKGAQET-IALVGKGIVYDTGGLS 411
             ..|..::..|:..|...|....|..|:|.||..:.|.:: |.|:.:| :||||||:.:|:||.:
plant   234 DVFTANILNEEQCKELKMGSYLAVAAASANPPHFIHLVYKPPNGSVKTKLALVGKGLTFDSGGYN 298

  Fly   412 IKAKTGMPG-----MKRDCGGAAAILGTFYAAVQCGFRD----NLHAVFCLAENSVGPNATRPDD 467
            |  ||| ||     ||.|.||:||:||   ||...|...    .:|.:....||.:.....||.|
plant   299 I--KTG-PGCSIELMKFDMGGSAAVLG---AAKAIGEIKPPGVEVHFIVAACENMISGTGMRPGD 357

  Fly   468 IHTLYSGRTVEINNTDAEGRLVLADGVCYA-NKDLKANIILDMATLTGAQGVATGKYHGAILTNS 531
            :.|..:|:|:|:|||||||||.|||.:.|| |:.:  :.|:|:||||||..:|.|.....|.|.|
plant   358 VITASNGKTIEVNNTDAEGRLTLADALVYACNQGV--DKIVDLATLTGACVIALGTSMAGIYTPS 420

  Fly   532 ETWEAKSLQAGRKSGDLL--APIIYCPELHFSEFASAIADMKNSVADRQNAQSSCAGLFIAAHLG 594
            :....:.:.|..:||:.|  .|:   .|.::....|.:|||.|:  ..:...|..|.||:...:.
plant   421 DELAKEVIAASERSGEKLWRMPL---EESYWEMMKSGVADMVNT--GGRAGGSITAALFLKQFVS 480

  Fly   595 FDYPGIWMHVDMATPVHCGER--ATGYGVSLLL 625
            ....  |||:|||.||...::  .||:||:.|:
plant   481 EKVQ--WMHIDMAGPVWNEKKKSGTGFGVATLV 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grsm	NP_731749.3	Peptidase_M17	141..628	CDD:238247	142/488 (29%)
LAP1	NP_001118375.1	PRK00913	20..516	CDD:234863	142/488 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780