Protein Alignment grsm and lap-1

DIOPT Version :9

• Sequence 1: NP_731749.3
• Gene: grsm / 41587
• FlyBaseID: FBgn0040493
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_498854.1
• Gene: lap-1 / 176185
• WormBaseID: WBGene00002249
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 503
• Identity: 217/503 - (43%)
• Similarity: 299/503 - (59%)
• Gaps: 39/503 - (7%)

  Fly   143 VLIIGQLRHLNLL----KFSHLESKLSPRVTEETFLNAVACLHPAPTDKVSLYLDVATVAALPLK 203
            ::|:|:...|..:    ||..:..|.   ||:....|::....|| :.:..|:.::|.:..:|..
 Worm    20 LIIVGKKSVLKNVTFEGKFKEVAQKF---VTDGDSWNSMISRIPA-SGRHPLHYELAHLITVPDA 80

  Fly   204 ASRHNTASRAHAITRLVK--NHVLNVSEESVVLVCERENLFASACAVVRAFPLYSRKTGNLLASS 266
            :||.||.:.||:|.:.:|  |:..:......||..|..::.:...|:.|.|..:|.||..:
 Worm    81 SSRGNTPTNAHSIYKELKPINYPEDTKNVHFVLFAEYPDVLSHVAAIARTFCKFSMKTSGI---- 141

  Fly   267 QPKLNLGCGDGNANSGRNVVNVEFVLINKDGCIESEPLTDDELNCLNETTRAIRMTARIVDMPCN 331
             .:||              ||::.|      |   :.||:::...|.:.:.::|.|||::|.|.|
 Worm   142 -RELN--------------VNIDVV------C---DKLTNEDAVFLTDLSESVRETARLIDTPAN 182

  Fly   332 EMNVDHFIQEVEDVGRELCITPKVIRGEELLEQGFGGIYGVGKAAAVPPALVVLSHEPKGAQETI 396
            .:..|..:.|...||........||||||||:.||||||.||||...|||.||||||..|:.|.|
 Worm   183 ILTTDALVDEAVKVGNATGSKITVIRGEELLKAGFGGIYHVGKAGPTPPAFVVLSHEVPGSTEHI 247

  Fly   397 ALVGKGIVYDTGGLSIKAKTGMPGMKRDCGGAAAILGTFYAAVQCGFRDNLHAVFCLAENSVGPN 461
            ||||||:|||||||.||.|||||.||||.||||.:|..:.|.|:.||...|||..|:.||:|.|.
 Worm   248 ALVGKGVVYDTGGLQIKTKTGMPNMKRDMGGAAGMLEAYSALVKHGFSQTLHACLCIVENNVSPI 312

  Fly   462 ATRPDDIHTLYSGRTVEINNTDAEGRLVLADGVCYANKDLKANIILDMATLTGAQGVATGKYHGA 526
            |.:||||..:.||:|||||||||||||:|||||.||.:.|||..|.|||||||||...:|:.|||
 Worm   313 ANKPDDIIKMLSGKTVEINNTDAEGRLILADGVFYAKETLKATTIFDMATLTGAQAWLSGRLHGA 377

  Fly   527 ILTNSETWEAKSLQAGRKSGDLLAPIIYCPELHFSEFASAIADMKNS-VADRQNAQSSCAGLFIA 590
            .:||.|..|.:.::||:.||||:||:::.|:|.|.:..|:||||||| :.......|:.|||||.
 Worm   378 AMTNDEQLENEIIKAGKASGDLVAPMLFAPDLFFGDLKSSIADMKNSNLGKMDGPPSAVAGLFIG 442

  Fly   591 AHLGFDYPGIWMHVDMATPVHCGERATGYGVSLLLTLFGGHTDSKLLQ 638
            ||:||.....|:|:|:|.|...|:|.||||.:|..||.|.:|...:|:
 Worm   443 AHIGFGEGLRWLHLDIAAPAEVGDRGTGYGPALFSTLLGKYTSVPMLK 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grsm	NP_731749.3	Peptidase_M17	141..628	CDD:238247	213/491 (43%)
lap-1	NP_498854.1	Peptidase_M17	35..480	CDD:238247	210/476 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167594
Domainoid	1	1.000	331	1.000	Domainoid score	I609
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11647
Inparanoid	1	1.050	370	1.000	Inparanoid score	I1231
Isobase	1	0.950	-	0	Normalized mean entropy	S3211
OMA	1	1.010	-	-		QHG55148
OrthoDB	1	1.010	-	-		D259062at33208
OrthoFinder	1	1.000	-	-		FOG0006189
OrthoInspector	1	1.000	-	-		oto18732
orthoMCL	1	0.900	-	-		OOG6_105603
Panther	1	1.100	-	-	LDO	PTHR11963
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1683
SonicParanoid	1	1.000	-	-		X3934
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790