DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp304a1 and CYP89A6

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_176674.1	Gene:	CYP89A6 / 842802	AraportID:	AT1G64940	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	556	Identity:	127/556 - (22%)
Similarity:	214/556 - (38%)	Gaps:	123/556 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ETLLTICAAVFLCLSYRYAVGRPSG------FPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSR 62
            |..|.|..::||.|...:.:.|...      .||.|...|..|:        .|:|.|....|..
plant     2 EIWLLILGSLFLSLLVNHLLFRRRDSFSSLPLPPDPNFFPFIGT--------LKWLRKGLGGLDN 58

  Fly    63 WYKSDIIGLHVGPFPVAVVHSADGV----------REILNNQVFDGRPQLFVAAMRDPGQDVRGI 117
            :.:|  :..|:||.....:.|...:          ..:||..||..||         |.:.:..|
plant    59 YLRS--VHHHLGPIITLRITSRPAIFVTDRSLAHQALVLNGAVFADRP---------PAESISKI 112

  Fly   118 FFQD---------GPLWK--------------------EQRRFILRYLRDFG-FGRRFDQLELVI 152
            ...:         |..|:                    ..||::|..|  || ||:...:..:|:
plant   113 ISSNQHNISSCLYGATWRLLRRNLTSEILHPSRLRSYSHARRWVLEIL--FGRFGKNRGEEPIVV 175

  Fly   153 QEQLN----DMLDLIRNGPKYPHEHEMVKSGGYRVLLPLL----FNPFSANAHF-YIVYNECLSR 208
            .:.|:    .:|.|:..|.|.  :.:.:|...|.....||    ||..:....| .::|.:  ..
plant   176 VDHLHYAMFALLVLMCFGDKL--DEKQIKQVEYVQRRQLLGFSRFNILTLWPKFTKLIYRK--RW 236

  Fly   209 EEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYL 273
            ||.            ||..::....:|.:|...|.|..|....:...|.:      ..::|..|:
plant   237 EEF------------FQMQSEQQDVLLPLIRARRKIVDERKKRSSEEEKD------NKEYVQSYV 283

  Fly   274 DSYEEGVERNFMDVYIAEMRRGPGYGFNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVL 338
            |:        .:||.:.:.:|    ..|.|:::....:|...........|..::..|:..|.:.
plant   284 DT--------LLDVELPDEKR----KLNEDEIVSLCSEFLNAGTDTTATALQWIMANLVKNPEIQ 336

  Fly   339 RRVQNEIDEVVG-CGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKD 402
            ||:..||..:|| ..:....:|.:.:|:.:|.:.||||........:||...|||.|.||::||.
plant   337 RRLYEEIKSIVGEEAKEVEEQDAQKMPYLKAVVMEGLRRHPPGHFVLPHSVTEDTVLGGYKVPKK 401

  Fly   403 TIVVPSLYAFHSDARIWSDPEQFRPERFL----DADGKLCLKLDVSLPFGAGKRLCAGETFARNM 463
            ..:...:.....|.::|.:|..|:||||:    |..|...:|:   :|||||:|:|.|...|...
plant   402 GTINFMVAEIGRDPKVWEEPMAFKPERFMEEAVDITGSRGIKM---MPFGAGRRICPGIGLAMLH 463

  Fly   464 LFLVTATMCQHFDF--VLGPNDRLPDLSQNLNGLII 497
            |....|.|.:.|::  |.|..   .||::.|...::
plant   464 LEYYVANMVREFEWQEVQGHE---VDLTEKLEFTVV 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	120/524 (23%)
CYP89A6	NP_176674.1	CYP77_89	68..502	CDD:410698	109/480 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000