DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp304a1 and CYP76C6

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_174633.1	Gene:	CYP76C6 / 840263	AraportID:	AT1G33720	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	136/517 - (26%)
Similarity:	230/517 - (44%)	Gaps:	84/517 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ETLLTICAAVFLCLSY------RYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSR 62
            :.|..|...:..||.:      |.:..:.|..|||||::|:.|:    :.:..|..|.:...||:
plant     7 QPLFLIFCFILSCLLFFTTARSRRSPCQLSKSPPGPPRLPIIGN----IHLVGKNPHHSFTDLSK 67

  Fly    63 WYKSDIIGLHVGPFPVAVVHSADGVREIL--NNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLW 125
            .| ..::.|.:|.....|:.|.|.|||:|  ::|:..||   :::..........   |..|.:.
plant    68 TY-GPVMSLKLGCLNSVVIASRDAVREVLKTHDQILSGR---YISEATKSNNHHE---FSVGWIH 125

  Fly   126 KEQRRFILRYLRDFGFGRRFD--------QLEL-VIQEQLNDMLDLIRNGPKYPHEHEMVKSGGY 181
            ....||  |.||.....:.|.        .|.: .:||.:|.:.:....     .|...:....:
plant   126 PSSSRF--RMLRKLSATQLFSPQCIQATKALRMKKVQELVNFLSESCER-----EEAVDISHVSF 183

  Fly   182 RVLLPLLFN-PFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQR---NADDYGKMLSIIPWIR 242
            ...|.::.| .||.|...|...|....:|          |.|.:|.   |.|    :.:..|::|
plant   184 VTALNIISNILFSVNLGSYDSKNSSAFQE----------MVIGYQESIGNPD----LANFFPFMR 234

  Fly   243 HIWPEWSGYN-KLNESNLFVRQFFADF-----VDKYLDSYEEGV-ERNFMDVYIAEMRRGPGYGF 300
            .:  :..|.: |:.||:..:.|.|.:|     |:|...|.|:.| .::|:||.| ::::|.....
plant   235 FL--DLQGNSKKMRESSGRLLQVFREFYDARIVEKSSRSVEKDVSSKDFLDVLI-DLQQGDETEI 296

  Fly   301 NRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLML----YPAVLRRVQNEIDEVVGCGRLPNLEDRK 361
            |.|::...|:|. |.|.|...   |..|::.|.    .|..:.:||:||:.|:|........|..
plant   297 NIDEIEHLLLDM-FVAGTDTN---SSTVEWAMAELLGNPKTMTKVQDEINHVIGQNGDFQESDIS 357

  Fly   362 NLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFR 426
            .||:.:|.::|..|:....|..:..||..:.|:||:.:.||:.|:.:::|...|..:|.:|..|.
plant   358 KLPYLKAVVKETFRLHPAAPFLLQRKAETNVEILGFTVLKDSQVLVNVWAIGRDPLVWENPTHFE 422

  Fly   427 PERFLDADGKLCLKLDVS------LPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPN 482
            |||||   ||   ::||.      .|||||:|:|.|...|...:.|:.|::...|::.| ||
plant   423 PERFL---GK---EIDVKGTDYELTPFGAGRRICPGLPLAMKTVHLMLASLLYTFEWKL-PN 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	130/485 (27%)
CYP76C6	NP_174633.1	p450	11..504	CDD:299894	135/513 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000