DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp304a1 and CYP71B28

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_172768.1	Gene:	CYP71B28 / 837866	AraportID:	AT1G13090	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	124/552 - (22%)
Similarity:	213/552 - (38%)	Gaps:	161/552 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FLCLSYRYAVG----RPSGF--PPGPPKIPLFGSYLFMLIINFKYLH-KAALTLSRWYKSDIIGL 71
            ||||.....:.    :||.:  ||||.|:|:.|:     :...:.|| :.:..||..| ..|:.|
plant     7 FLCLLPLILIFLKNLKPSKWKLPPGPKKLPIIGN-----LHQRRELHPRNSRNLSEKY-GPIVFL 65

  Fly    72 HVGPFPVAVVHSADGVREILNNQVFD--GRPQLFVAAMRDPGQDVRGIFFQD-GPLWKEQRRFIL 133
            ..|..||.|:.|.:...|:|.....:  .||:  ....|....:.:.|.|.. |..|:..|:..:
plant    66 RYGFVPVVVISSKEAAEEVLKTHDLECCSRPE--TVGTRAISYNFKDIGFAPYGEDWRTMRKLSV 128

  Fly   134 ------------RYLRD------------------------------------FGFGRRFDQLEL 150
                        ||:|:                                    .|||....:.|.
plant   129 VELFSSKKLQSFRYIREEENDLCVKKLSDLASRRSLVNLEKTLFTLVGSIVCRIGFGINLRECEF 193

  Fly   151 VIQEQLNDML----DLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEM 211
            |.::.::|::    |:|||.                     :|:.|....              |
plant   194 VDEDSIDDLVHKSEDVIRNS---------------------IFSDFFPGL--------------M 223

  Fly   212 GKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSY 276
            |:|::                       ||      :|...:||.....|..||.:.:|.:|...
plant   224 GRLIE-----------------------WI------FSERKRLNRLYSEVDTFFQNILDDHLKPG 259

  Fly   277 EEGVERNFMDVYIAEMRR----GPGYGFNRDQLIMGLVDFSFPAFTAIGVQLSLLV---QYLMLY 334
            .|  ..:.:||.|..|::    |..:.|..|.| .|::...|.|  .:|...:.|:   ..|:..
plant   260 RE--SSDIIDVMIDMMKKQEKEGDSFKFTTDHL-KGMISDIFLA--GVGTSSTTLIWAMTELIRN 319

  Fly   335 PAVLRRVQNEIDEVVG--CGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGY 397
            |.|:::||:||...:|  ..|:.. ||...|.:.:..::|..|:....|..:|.:.|...::.||
plant   320 PRVMKKVQDEIRTTLGDKKERITE-EDLNQLHYFKLMVKEIFRLHPAAPLLLPRETLSHVKIQGY 383

  Fly   398 RIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVS------LPFGAGKRLCAG 456
            .||..|.::.:.||...|.::|::|::|.|:||||:      .:|..      ||||:|:|:|.|
plant   384 DIPAKTQIMINAYAIARDPKLWTNPDEFNPDRFLDS------SIDYRGLNFELLPFGSGRRICPG 442

  Fly   457 ETFARNMLFLVTATMCQHFDFVLGPNDRLPDL 488
            .|....::.|....:...||:.|...:...::
plant   443 MTMGIAIVELGLLNLLYFFDWGLPEKEEAKEI 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	118/530 (22%)
CYP71B28	NP_172768.1	CYP71-like	58..474	CDD:410695	107/494 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000