DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp304a1 and CYP71B13

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_197896.1	Gene:	CYP71B13 / 832585	AraportID:	AT5G25140	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	121/514 - (23%)
Similarity:	217/514 - (42%)	Gaps:	57/514 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 AAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYL----HKAALTLSRWYKSDIIGL 71
            |::|:..:.|..   ....|||||::|:.|        |...|    |::...||..| ..::.|
plant    14 ASIFIAKNTRKT---KKNLPPGPPRLPIIG--------NLHQLGSKPHRSMFKLSEKY-GPLVYL 66

  Fly    72 HVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQD-GPLWKEQRRFILRY 135
            .:|..|..|..:.:.|:::|.....|...:.|:........:::.:.|.. ...||..|:..:..
plant    67 KLGKVPSVVASTPETVKDVLKTFDKDCCSRAFLTYPARISYNLKDLAFAPYSKYWKAVRKMTVVE 131

  Fly   136 LRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPH----EHEMVKSGGYRVLLPLLFNPFSANA 196
            |..   .:|......:.:|::...::.|::......    ...:||..| .|:..:.|......:
plant   132 LYT---AKRVKSFRNIREEEVASFVEFIKHSASLEEIVNLNQTLVKLSG-SVICRVGFGINLEGS 192

  Fly   197 HFYIVYNECL--SREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSG-YNKLNESN 258
            .....|.|.:  :.|.:|...            |.||      .|.|..|....:| :||..:..
plant   193 KLENTYEEVIHGTMEVLGSFA------------ASDY------FPVIGGIIDRITGLHNKCEKVF 239

  Fly   259 LFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRRGPGYG---FNRDQLIMGLVDFSFPAFTAI 320
            .....||...:..:|:  :.|.:.:.:|:.:...|...|.|   |.|:.....|:|.........
plant   240 KGTDSFFDHCIKHHLE--DGGSKDDIVDLLLKVERGEIGLGEFQFTRNHTKGILLDILLAGVDTS 302

  Fly   321 GVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVP 385
            |..::.::.:|:..|.|:::.|.|:.||:........||.:.|.:.:..::|.|||..|||...|
plant   303 GHTITWVMTHLIKNPRVMKKAQAEVREVIKNKDNITEEDIEGLEYLKMVVKETLRINPLVPLLTP 367

  Fly   386 HKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLD--ADGK-LCLKLDVSLPF 447
            .:|.:|.::.||.|||.|.:..:::|.|.:..:|.|||.|.||||:|  .|.| |..:|   |||
plant   368 REASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVWKDPEAFIPERFMDNQIDYKGLNFEL---LPF 429

  Fly   448 GAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQL 506
            |:|:|:|.|......::.|....:...||:.|.....:.|:....:..::.|....|:|
plant   430 GSGRRICPGIGMGMALIHLTLINLLYRFDWKLPEGMEVEDVDLEESYGLVCPKKVPLEL 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	116/491 (24%)
CYP71B13	NP_197896.1	p450	1..490	CDD:299894	121/514 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000