DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp304a1 and CYP81K2

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_196622.2	Gene:	CYP81K2 / 830925	AraportID:	AT5G10600	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	121/501 - (24%)
Similarity:	189/501 - (37%)	Gaps:	80/501 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSDIIG 70
            |||.....|:.   ::...:....||.|..:|:.|   .:.:||...|.:|...||..| ..::.
plant    26 LLTATLTFFIT---KFLWSQNPKLPPSPTPLPIIG---HLHLINKYPLPQALHHLSSNY-GPVLF 83

  Fly    71 LHVGPFPVAVVHSADGVREILNNQ--VFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFIL 133
            |..|...|.::.|.|.:.|...|.  ....||:...:.....|....| |...|.||:..||  |
plant    84 LKFGCREVLILSSPDSIEECFTNHDIALANRPKTITSDHFSYGYKNFG-FAPYGDLWRTLRR--L 145

  Fly   134 RYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGG--YRVLLPLLFNPFSANA 196
            ..|..|..........:..:|..|....|.|            .|||  .:|.|...|...:|:.
plant   146 STLEVFSSVSLQKNSSIRTEEVSNLCSSLFR------------FSGGNSCKVDLRYQFTLLTAHV 198

  Fly   197 HFYIV-----YNECLSREEMGKL--------VKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEW 248
            ...:|     .||..|..|...|        ..|..|      |..||      .|.:|     |
plant   199 MLRLVSGNRGVNESDSESETKFLDEFKSRFFSSLSSM------NVCDY------FPVLR-----W 246

  Fly   249 SGYNKLNESNLFVRQFFADFVDKYLDSYE-------EGVERNFMDVYIAEMRRGPGYGFNRDQLI 306
            .||..|....:.:::...:::.:.:|...       ..|...|:.:..:|..      |..|.:|
plant   247 IGYKGLENRVIEIQRMRDEYLQRLIDDIRMKKFDSTGSVVEKFLKLQESEPE------FYSDDVI 305

  Fly   307 MGLVDFSFPAFTAIG-VQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATI 370
            .|:|...|.|.:... |.:...:..|:.:|..|.:|:.||...|....:....|..:||:....|
plant   306 KGIVVLMFNAGSDTSPVTMEWAMALLLNHPDKLDKVREEIKSNVKHKGIIQDSDLSSLPYLRCVI 370

  Fly   371 REGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFL---- 431
            .|.||:....|...||.:.:...|..|.||::|:::.:.:|.|.|..:|.:.:.|:||||.
plant   371 YETLRLHPAAPILPPHCSSKRFNLGNYEIPENTVLLVNAWAVHRDGELWEEADVFKPERFEEFVG 435

  Fly   432 DADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDF 477
            |.||..      .||||.|:|.|.....|..::.|....:.|.|::
plant   436 DRDGFR------FLPFGVGRRACPAAGLAMRVVSLAVGALVQCFEW 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	117/477 (25%)
CYP81K2	NP_196622.2	p450	18..511	CDD:299894	121/501 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000