DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp304a1 and CYP81D8

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_195453.1	Gene:	CYP81D8 / 829891	AraportID:	AT4G37370	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	131/507 - (25%)
Similarity:	212/507 - (41%)	Gaps:	89/507 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MITETLLTICAAVFLCLSYRYAVG---RPSGFPPGPP-KIPLFGSYLFMLIINFKYLHKAALTLS 61
            |.|:||  |.:.:|:.||..|.:|   |....||.|. .:|:.| :|.:|   ...:|:..|:||
plant     1 METKTL--IFSILFVVLSLIYLIGKLKRKPNLPPSPAWSLPVIG-HLRLL---KPPIHRTFLSLS 59

  Fly    62 R-WYKSDIIGLHVGPFPVAVVHSADGVRE---ILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDG 122
            : ...:.|..|.:|. .:..|:|:..:.|   ..|:.|...||. |:.|..........|....|
plant    60 QSLNNAPIFSLRLGN-RLVFVNSSHSIAEECFTKNDVVLANRPN-FILAKHVAYDYTTMIAASYG 122

  Fly   123 PLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLD------------LIRNGPKYPHEHEM 175
            ..|:..              ||...:|:....:||..|.            |.||     ...|.
plant   123 DHWRNL--------------RRIGSVEIFSNHRLNSFLSIRKDEIRRLVFRLSRN-----FSQEF 168

  Fly   176 VKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNAD-----DYGKML 235
            ||.....:|..|.||...........|.:.:..:...|.|:        |..||     ..|..:
plant   169 VKVDMKSMLSDLTFNNILRMVAGKRYYGDGVEDDPEAKRVR--------QLIADVVACAGAGNAV 225

  Fly   236 SIIPWIRHIWPEWSGY--------NKLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEM 292
            ..:|.:|.:    |.|        .:|:|       |....||:..::.|:|  ...:|..:...
plant   226 DYLPVLRLV----SDYETRVKKLAGRLDE-------FLQGLVDEKREAKEKG--NTMIDHLLTLQ 277

  Fly   293 RRGPGYGFNRDQLIMG-LVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPN 356
            ...|.| |. |::|.| ::...........|.|...:..::.:|.||.:.::|||..:|..||.:
plant   278 ESQPDY-FT-DRIIKGNMLALILAGTDTSAVTLEWALSNVLNHPDVLNKARDEIDRKIGLDRLMD 340

  Fly   357 LEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSD 421
            ..|..|||:.:..:.|.||:....|..:||.|.||.::.||.:|:.||::.:::|.|.|.::|.|
plant   341 ESDISNLPYLQNIVSETLRLYPAAPMLLPHVASEDCKVAGYDMPRGTILLTNVWAIHRDPQLWDD 405

  Fly   422 PEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQ 473
            |..|:|||| :.:|: ..||   :|||.|:|.|.|...|..::.|...::.|
plant   406 PMSFKPERF-EKEGE-AQKL---MPFGLGRRACPGSGLAHRLINLTLGSLIQ 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	120/475 (25%)
CYP81D8	NP_195453.1	p450	5..487	CDD:299894	129/503 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000