DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp304a1 and CYP76G1

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001190075.1	Gene:	CYP76G1 / 824463	AraportID:	AT3G52970	Length:	530	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	136/541 - (25%)
Similarity:	220/541 - (40%)	Gaps:	102/541 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TICAAVFL-CLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYL--HKAALTLSRWYKSDII 69
            :|...::: ||.|....  .:..||||...|:.|:     |.....|  |.:...|||.: ..|:
plant    16 SIAVLIYVTCLFYTKRC--RTRLPPGPNPWPVIGN-----IFQLAGLPPHDSLTKLSRRH-GPIM 72

  Fly    70 GLHVGPFPVAVVHSADGVREIL--NNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFI 132
            .|.:|.....|:.|::..|||.  ::....|| :::.|.......|...|..|.|..|:..||..
plant    73 TLRIGSMLTVVISSSEVAREIFKKHDAALAGR-KIYEAMKGGKSSDGSLITAQYGAYWRMLRRLC 136

  Fly   133 LRYLRDFGFGRRFDQLELVIQEQLNDMLDLI----RNGPKYPHEHEM--------VKSGGYRVLL 185
               ...|...||.|.:..|....::.||..:    :||..|...:.|        :..|.|..|:
plant   137 ---TTQFFVTRRLDAMSDVRSRCVDQMLRFVEEGGQNGMYYTINNIMTCIICTKTIDVGRYFFLM 198

  Fly   186 PLLFNPFSANAHFYIVYNECLSRE--------------EMGKLVKLCQMGIQFQRNADDYGKMLS 236
            .           |.::.|...||:              ..||:::...     :.|..|:
plant   199 A-----------FNLIGNLMFSRDLLDPDSKRGSEFFYHTGKVMEFAG-----KPNVADF----- 242

  Fly   237 IIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVER--------NFMDVYIAEMR 293
             .|.:|.:.|:  |..:  ::...|.:.| :...:::....|..||        :::|| :.|.|
plant   243 -FPLLRFLDPQ--GIRR--KTQFHVEKAF-EIAGEFIRERTEVREREKSDEKTKDYLDV-LLEFR 300

  Fly   294 RGPGYG------FNRDQLIMGLVDFSFPAFTAIGVQ-----LSLLVQYLMLYPAVLRRVQNEIDE 347
            .|.|..      .:||..::     .|..||| |..     |...:..|:..|..|.::|.|:..
plant   301 GGDGVDEEPSSFSSRDINVI-----VFEMFTA-GTDTTTSTLEWALAELLHNPRTLTKLQTELRT 359

  Fly   348 VV-GCGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLG-YRIPKDTIVVPSLY 410
            .. ...:....||..|||:..|.|.|.||:...:|..|||||:....:.. |.|||:|.|:.:::
plant   360 YFKSSNQKLQEEDLPNLPYLSAVIMETLRLHPPLPFLVPHKAMSTCHIFDQYTIPKETQVLVNVW 424

  Fly   411 AFHSDARIWSDPEQFRPERFL-DADGKLCLKLDVS-LPFGAGKRLCAGETFARNMLFLVTATMCQ 473
            |...|.:.|.||..|:||||: |.|.:.....|.. ||||:|:|:|.....|..:|.|...:|.:
plant   425 AIGRDPKTWIDPIMFKPERFISDPDARDFKGQDYEFLPFGSGRRMCPALPLASRVLPLAIGSMVR 489

  Fly   474 HFDFVL--GPNDRLPDLSQNL 492
            .||:.|  |.|....|:.:.:
plant   490 SFDWALENGLNAEEMDMGERI 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	132/518 (25%)
CYP76G1	NP_001190075.1	p450	13..526	CDD:299894	136/541 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000