DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp304a1 and CYP71A21

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_680111.1	Gene:	CYP71A21 / 823990	AraportID:	AT3G48320	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	141/515 - (27%)
Similarity:	238/515 - (46%)	Gaps:	93/515 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYL----HKAALTLS 61
            :|.::|:.....:|.....|   |:.|..|..||::||.|        |...|    |::..:||
plant     7 IILQSLIIFITILFFKKQKR---GKKSNTPRSPPRLPLIG--------NLHQLGHHPHRSLCSLS 60

  Fly    62 RWYKSDIIGLHVGPFPVAVVHSADGVREIL--NNQVFDGRP--QLFVAAMRDPGQDVRGIFFQDG 122
            ..| ..::.||:|..||.||.|||..|:||  :::||..||  :||.....| |:||  .|...|
plant    61 HRY-GPLMLLHLGRVPVLVVSSADVARDILKTHDRVFASRPRSKLFEKLFYD-GRDV--AFAPYG 121

  Fly   123 PLWKEQRRF-ILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRV--- 183
            ..|::.:.. :||.|.:    :.......|.||:::.|::.|:            ||...:|
plant   122 EYWRQIKSVCVLRLLSN----KMVTSFRNVRQEEISLMMEKIQ------------KSSSLQVNVS 170

  Fly   184 -LLPLLFNPFSANAHFYIVYN-ECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWP 246
             ||..|.|...:.......|: |..|:|.|.:|:.|  || :|        .:.:.:||:.  |.
plant   171 ELLGSLTNDVISRIALGRKYSGETDSKELMKRLMML--MG-EF--------SVGTYVPWLG--WI 222

  Fly   247 EW-SGYN-KLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRRGPGYGFNRDQLIMGL 309
            :| ||.: :||::...:.:|....|..::|.  :|...:|:|| :..::|....||..|:|.:..
plant   223 DWISGLDGQLNKTGNDLDEFLEKVVQDHVDG--DGQRTDFVDV-LLRIQREKSIGFEIDRLCIKA 284

  Fly   310 V---------DFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPF 365
            :         |.|:       ..:...:..|:.:|..||.:|.|:..:.......:.||.:|:.:
plant   285 IVLDVLVAGTDSSY-------ALMDWAMTELLRHPECLRTLQEEVRTICKGNLSVSEEDIQNMSY 342

  Fly   366 TEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWS-DPEQFRPER 429
            .:|.|:|..|:...:|...||::::|..|..|.||..|.|:.:.:|...:|..|. |.|:|||||
plant   343 LKAVIKETTRLHPPLPLLAPHESIQDVILGDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPER 407

  Fly   430 FLDADGKLCLKLDVS------LPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPND 483
            .||:      .:|..      :|||||:|:|...:||..::.:..|.....:|:.| |.|
plant   408 HLDS------SVDFRGHNFELVPFGAGRRICPAISFAVVLIEVALANFVHRYDWKL-PED 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	135/486 (28%)
CYP71A21	NP_680111.1	p450	1..482	CDD:299894	141/515 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000