DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp304a1 and CYP705A22

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_188648.1	Gene:	CYP705A22 / 821556	AraportID:	AT3G20130	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	133/544 - (24%)
Similarity:	221/544 - (40%)	Gaps:	90/544 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LTICAAVFLCLSYRYAVGRPS----GFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSD 67
            :.|....|||..:.:...:.|    ..||.||.:|:.| ::.:|:...  .||:...||..| ..
plant    16 ILIFLLTFLCFFFFFKKPKDSRVNFDLPPSPPSLPIIG-HVHLLLSTL--THKSLQKLSSRY-GP 76

  Fly    68 IIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFI 132
            ::.|.:...|:.:|.||....||...|              |.....||:...|..|......|:
plant    77 LLYLRIFNVPIILVSSASVAYEIFRTQ--------------DVNISSRGVTAVDESLVFGSSSFV 127

  Fly   133 LRYLRDF-GFGRRFDQLELV---IQEQ-----LNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLL 188
            .....|: .|.::...::|:   .|||     .:|:....||......:.|.|:.|  :..:.|:
plant   128 TAPYGDYWKFMKKLTVMKLLGPQAQEQSRDIRADDIKRFCRNLLDKARKKESVEIG--KEAMNLM 190

  Fly   189 FNPFSANAHFYIVYNECLSR---EEMGKLVKLCQMGIQFQRNADDYG---KMLSIIPWIRHIWPE 247
            .|         |:....:.|   ||.|:..||  .|:.    .:..|   ||...:...|.:  :
plant   191 NN---------ILCKMSMGRSFSEENGETEKL--RGLV----TESIGLMKKMFLAVLLRRQL--Q 238

  Fly   248 WSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVERN----FMDVYIAEM-RRGPGYGFNRDQLIM 307
            ..|.:...:..:.|...|...::|.|..:.|..|::    .:||.:|.. .....|...::.:..
plant   239 KLGISLFKKDIMGVSNKFDVLLEKVLVEHREKPEKDQGTVMLDVLLAAYGDENAEYKITKNHIKA 303

  Fly   308 GLVDFSFPAFTAIGVQ-LSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIR 371
            ..||. |...|...|| :...:..:|....:|.|::.|||.|||..||....|..|||:..|.|:
plant   304 FFVDL-FIGATDTSVQTIQWTMAEIMNNTHILERMREEIDSVVGKSRLIQETDLPNLPYLHAVIK 367

  Fly   372 EGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFL----- 431
            |.||:....|. :|.:..:..::.|:.||:.|.::.:.|....|..:|.|||:|:|||||
plant   368 EALRLHPPGPL-LPREFQQGCKIGGFYIPEKTTLLINAYVVMRDPNVWEDPEEFKPERFLASSRS 431

  Fly   432 ---DADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLN 493
               |...:..||.   ||||:|:|.|.|...|..::......|.|.||:.:  .....::.:.:.
plant   432 GQEDERREQALKF---LPFGSGRRGCPGSNLAYMIVGSAIGMMVQCFDWRI--EGEKVNMKEAVK 491

  Fly   494 GLIIS-------------PPDFWL 504
            |.|::             ||..|:
plant   492 GTILTMAHPLKLTPVTRQPPLTWI 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	127/515 (25%)
CYP705A22	NP_188648.1	CYP93	75..505	CDD:410748	113/469 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000